[risk factors of leishmanin-skin test positivity in transmission of leishmania infantum in the center of tunisia].this work aims to estimate prevalence and evaluate risk factors of leishmanin-skin test positivity. a cross-sectional leishmanin skin test study was carried out on a sample of 3190 healthy volunteers living in the gouvernorates of kairouan and kasserine. age standardized prevalence of leishmanin-skin test positivity was 45.9% (ci95% = [43.9-47.9]) confirming the hyper endemicity of this region. the rate of leishmanin-skin test positivity ranged from 75.9% (ci95% = [71.9-79.5]) in zaghdoud (kairo ...200315941064
interaction between canine and human visceral leishmaniases in a holoendemic focus of central tunisia.canine visceral leishmaniasis (cvl) is endemic in the mediterranean basin. in tunisia, cvl is spatially associated with human visceral leishmaniasis (hvl) affecting mostly children younger than 5 years old. in this study, seroprevalence of leishmania infantum infection in dogs was assessed in highly endemic districts of the governorate of kairouan where more than 50% of hvl cases in tunisia were reported. an entomological investigation was also carried out in two endemic districts (bouhajla and ...201425004438
[epidemiology of leishmania (l.) infantum, l. major and l. killicki in tunisia: results and analysis of the identification of 226 human and canine isolates].the epidemiological situation of leishmaniasis in tunisia is characterised by the co-existence in a very limited territory (165,000 km2, sahara included), of 4 clinical forms: the infantile visceral leishmaniasis (vl) and 3 cutaneous leishmaniasis (cl) forms (sporadic, zoonotic and chronic). in addition to the useful epidemiological data, identification of the causative parasitic species is essential to determine the geographic distribution of each form and to select appropriate therapeutic proc ...200818956815
leishmaniasis in central and southern tunisia: current geographical distribution of zymodemes.the authors report the identification of leishmania strains isolated from the centre and the south of tunisia. 266 strains were isolated between 1998 and 2006 from human (n=221 strains) and dogs (n=45 strains) hosts. the isoenzymatic identification exhibits the presence of in total five zymodemes belonging to three leishmanio complexes: leishmania infantum, l. major and l. killicki. all strains isolated from human and canine visceral leishmaniasis belonged to l. infantum. zymodeme mon-1 was the ...200717933302
[cutaneous leishmaniasis caused by leishmania infantum mon-24 in tunisia: extension of the focus to the center of the country].three clinico-epidemiological forms of cutaneous leishmaniasis (cl) were described in tunisia: the zoonotic cl (zcl) epidemic which occurred in the centre of the country caused by leishmania major mon-25, the chronic cl (ccl) in the south-east of the country caused by leishmania killicki mon-8 and the sporadic cl in the north (scl) caused by leishmania infantum mon-24. the latter form, described in 1991, prevails in northern tunisia with approximately thirty cases per year. its vector, unknown f ...200818432004
presence of sandfly-borne phleboviruses of two antigenic complexes (sandfly fever naples virus and sandfly fever sicilian virus) in two different bio-geographical regions of tunisia demonstrated by a microneutralisation-based seroprevalence study in dogs.sandfly-borne phleboviruses are present in north africa where they can infect humans in regions where leishmania infantum, the causative agent of zoonotic visceral leishmaniasis in the western mediterranean basin is present affecting both humans and dogs. we investigated the capacity of dogs to be used as sentinels for sandfly-borne phleboviruses as previously shown for leishmaniasis.201425306250
[epidemiological, clinical and biological features of infantile visceral leishmaniasis at kairouan hospital (tunisia): about 240 cases].visceral leishmaniasis (vl) is an important health problem in tunisia. it is most common in children under five years of age. the governorate of kairouan (central tunisia) is one of the most affected foci. the aim of this study was to update the epidemiological, clinical and biological features of the disease. the study concerned all vl cases admitted in the pediatric department of kairouan hospital during 10 years (from 2004 to 2013). for every patient included in this study and when available, ...201526168849
use of pcr, ifat and in vitro culture in the detection of leishmania infantum infection in dogs and evaluation of the prevalence of canine leishmaniasis in a low endemic area in tunisia.the aim of this study was to assess the use of parasitological, serological and molecular methods for the detection of leishmania infection in blood of 67 dogs and to investigate the prevalence of canine leishmaniasis (canl) in kairouan (central tunisia), an area known to be of reduced endemicity and has not been studied since 1973. veterinarians clinically examined all dogs, and the titer of anti-leishmania antibodies was determined by indirect immune-fluorescence antibody test. the presence of ...200919353954
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