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Description of macrolide-resistant and potential virulent clones of Streptococcus pyogenes causing asymptomatic colonization during 2000-2006 in the Lisbon area.The asymptomatic oropharyngeal colonization rate by Streptococcus pyogenes was 10.7% in children (901 among 8,405 children 0-16 years old) and 3.3% in adults (37 among 1,126 households of children) in the Lisbon area during 2000-2006. Macrolide-resistant S. pyogenes from children (n?=?149) was variable with time: 9.8-10.7% in 2000-2002, 28.1% in 2003, 19.6-2.7% in 2004-2005 and 14.6% in 2006. Eight lineages (97.3% of isolates) were identified based on at least 80% similarity of PFGE patterns, T ...201122012657
resistance to bacitracin in streptococcus pyogenes from oropharyngeal colonization and noninvasive infections in portugal was caused by two clones of distinct virulence genotypes.during 2000-2007 in lisbon, we identified 45 bacitracin-resistant streptococcus pyogenes isolates among 1629 isolates: 24 from oropharyngeal healthy carriers (out of 1026), 21 from patients with noninvasive infections (out of 559) and zero from invasive infections (out of 44). forty-four of those isolates, mainly of colonization, are low-level bacitracin-resistant members of the cmls(b)-macrolide-resistant and tetracycline-susceptible emm28/st52 clone previously detected in europe, but only amon ...200919486163
group a streptococci from carriage and disease in portugal: evolution of antimicrobial resistance and t antigenic types during 2000-2002.in this study, we analyzed the antimicrobial resistance properties and t antigenic types of 511 isolates collected in lisbon district, portugal, from throat swabs of healthy subjects (n=341), during 2000-2002 and from diverse infection sites (n=170) of outpatients and inpatients, during 1999-2002. erythromycin resistance was higher in tonsillitis/pharyngitis (27.4%) and skin infection isolates (21.1%), than in carriage and invasive isolates (<or=10%). differences in erythromycin resistance among ...200516359196
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