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decline in haemophilus influenzae type b meningitis--seattle-king county, washington, 1984-1989.the first vaccines licensed in the united states for prevention of haemophilus influenzae type b (hib) disease were composed of the capsular polysaccharide of hib, polyribosylribitol phosphate (prp). the vaccines, licensed in 1985, were moderately effective in preventing hib disease in children aged 24-59 months. in december 1987, the first hib conjugate vaccine was licensed. the vaccine was recommended for use in children aged 18-59 months to prevent meningitis and other forms of invasive disea ...19902123516
bacterial meningitis in the united states, 1986: report of a multistate surveillance study. the bacterial meningitis study group.a prospective, laboratory-based surveillance project obtained accurate data on meningitis in a population of 34 million people during 1986. haemophilus influenzae was the most common cause of bacterial meningitis (45%), followed by streptococcus pneumoniae (18%), and neisseria meningitidis (14%). rates of h. influenzae meningitis varied significantly by region, from 1.9/100,000 in new jersey to 4.0/100,000 in washington state. the overall case fatality rates for meningitis were lower than those ...19902230261
interannual variation of the incidence of haemophilus influenzae type b meningitis.we conducted a population-based retrospective cohort study to define the annual age-specific incidence of haemophilus influenzae type b meningitis for birth to 5-year-old residents of king county, washington, from january 1977 through december 1986. we found naturally occurring wide interannual variations in incidence. the standard deviations of the age-specific incidence during the eight years before the introduction of h influenzae vaccine varied from 26% to 115% of the mean. if short-term cha ...19892784511
Washington state pediatricians' attitudes toward alternative childhood immunization schedules.To determine the frequency of parents' requests for alternative childhood immunization schedules (ACISs) and pediatricians' comfort with and willingness to use ACISs.201122123877
the increasing incidence of ampicillin-resistant haemophilus influenzae. a cause of otitis media.middle ear exudate was obtained by myringotomy or aspiration from 625 suburban children, aged 1 month to 12 years, who had acute otitis media; bacterial pathogens were isolated from 71%. haemophilus species were isolated from 212 (29%), and streptococcus pneumoniae from 205 (28%). from 1975 to august 1977, the number of haemophilus isolates found to be resistant to ampicillin has appreciably increased. currently, 8% of all cases of acute otitis media in the washington, dc, area are due to h infl ...197822767
reemergence of the natural history of otolaryngologic infections: lessons learned from 2 american presidents.presidents george washington and theodore roosevelt suffered complications of epiglottitis and otomastoiditis, respectively. the introduction of antibiotics and vaccinations against haemophilus influenzae and streptococcus pneumoniae has significantly reduced the incidence of these otolaryngologic infections, such that the natural history of the disease is rarely encountered. however, antibiotic resistance and pathogenic evolution has raised concern about increased virulence of these common orga ...201728585510
low-income minority mothers' reports of infant health care utilisation compared with medical records.this study aimed to investigate mothers' reporting of the nature, location, frequency and content of health care visits for their infants, as compared with data abstracted from the infants' medical records. it was part of a community-based parenting intervention designed to improve preventive health care utilisation among minority mothers in washington, dc. mothers >or=18 years old with newborn infants and with poor or no prenatal care were enrolled in the study. a total of 160 mother-infant dya ...200717439537
secondary haemophilus influenzae type b in day-care facilities. risk factors and prevention.the risk factors for acquisition of secondary day-care-associated haemophilus influenzae type b disease were evaluated in a cohort of children in seattle-king county, washington; atlanta; and the state of oklahoma. during the study period, 129 primary cases were identified in children less than 5 years old who attended day-care facilities. in ten instances (8%), a secondary case occurred between one and 60 days after a primary case in the same classroom. risk of secondary disease in classroom co ...19853874293
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