| [effect of conjugated prp vaccines on the incidence of invasive diseases caused by haemophilus influenzae type b in childhood]. | prior to the introduction of conjugate vaccines, haemophilus influenzae type b (hib) was the leading cause of severe invasive infections in young children, in switzerland as in other countries. from 1976 to 1990, 150 children were treated for hib meningitis at the children's hospital of lucerne, corresponding to an annual incidence of 9.2 cases per 100,000 children aged under 15 years. in the same time period, the case fatality rate for meningitis was 4%. 87.3% of the meningitis cases occurred a ... | 1994 | 8184297 |