Publications

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ampicillin-resistant haemophilus in western australia. 1977302389
murray valley encephalitis acquired in western australia.to report a recent fatal case of encephalitis associated with evidence of murray valley encephalitis virus infection, only the second fatality from this infection in western australia.19911645843
bacterial meningitis in children under five years of age in western australia.to describe the epidemiology and the associated mortality and serious neurological sequelae of bacterial meningitis in children under five years of age in western australia, and to consider the potential impact of a haemophilus influenzae type b vaccine on this group of children.19911875809
brazilian purpuric fever in western australia. 19892785636
helping doctors to draw appropriate inferences from the analysis of medical studies.most clinicians and many medical statisticians interpret standard frequentist confidence intervals by invoking the bayesian concept of subjective probability. fortunately, the assumptions that render this interpretation acceptable are often quite reasonable in the setting of the practical day-to-day analysis of medical data. this article takes the subjective interpretation of confidence intervals to its logical conclusion and argues that the inferential understanding of clinicians and public hea ...19947997704
hib vaccination uptake in long-term day care centres in the pilbara. 19938336625
measuring the impact of conjugate vaccines on invasive haemophilus influenzae type b infection in western australia.haemophilus influenzae type b (hib) causes serious infections in 26-59 per 100,000 non-aboriginal australian children under five years of age. aboriginal children suffer much higher rates of infection (> or = 150 per 100,000), and at an earlier age, and have a greater risk of death and disability due to hib infection. in 1992 and 1993, four conjugate hib vaccines were introduced in australia, and a nationally funded program of infant vaccination was begun in july 1993. this study aimed at evalua ...19989599855
australia's notifiable diseases status, 2001: annual report of the national notifiable diseases surveillance system.in 2001 there were 104,187 notifications of communicable diseases in australia reported to the national notifiable diseases surveillance system (nndss). the number of notifications in 2001 was an increase of 16 per cent of those reported in 2000 (89,740) and the largest annual total since the nndss commenced in 1991. in 2001, nine new diseases were added to the list of diseases reported to nndss and four diseases were removed. the new diseases were cryptosporidiosis, laboratory-confirmed influen ...200312725505
upper respiratory tract bacterial carriage in aboriginal and non-aboriginal children in a semi-arid area of western australia.streptococcus pneumoniae, haemophilus influenzae and moraxella catarrhalis are associated with otitis media (om). indigenous children experience particularly high rates of om. few studies worldwide have described upper respiratory tract (urt) carriage in indigenous and non-indigenous children living in the same area.200616940834
the bacteriology of pneumonia diagnosed in western australian emergency departments.we used western australian emergency department data linked to hospital morbidity, death and microbiology data to describe the bacteriology of pneumonia according to age. the 'atypical' organisms and viruses were not assessed. a total of 6908 patients over a 3-year period were given an emergency department diagnosis of pneumonia, 76.9% were admitted and 6.3% died in hospital. blood was cultured from 52.9% of patients with 6.4% growing potential pathogens. streptococcus pneumoniae was the most co ...200717274861
diversity of nontypeable haemophilus influenzae strains colonizing australian aboriginal and non-aboriginal children.nontypeable haemophilus influenzae (nthi) strains are responsible for respiratory-related infections which cause a significant burden of disease in australian children. we previously identified a disparity in nthi culture-defined carriage rates between aboriginal and non-aboriginal children (42% versus 11%). the aim of this study was to use molecular techniques to accurately determine the true nthi carriage rates (excluding other culture-identical haemophilus spp.) and assess whether the nthi st ...201424501028
vaccine preventable diseases and vaccination coverage in aboriginal and torres strait islander people, australia 2006-2010.this report outlines the major positive impacts of vaccines on the health of aboriginal and torres strait islander people from 2007 to 2010, as well as highlighting areas that require further attention. hepatitis a disease is now less common in aboriginal and torres strait islander children than in their non-indigenous counterparts. hepatitis a vaccination for aboriginal and torres strait islander children was introduced in 2005 in the high incidence jurisdictions of the northern territory, quee ...201324410428
high nasopharyngeal carriage of non-vaccine serotypes in western australian aboriginal people following 10 years of pneumococcal conjugate vaccination.invasive pneumococcal disease (ipd) continues to occur at high rates among australian aboriginal people. the seven-valent pneumococcal conjugate vaccine (7vpcv) was given in a 2-4-6-month schedule from 2001, with a 23-valent pneumococcal polysaccharide vaccine (23vppv) booster at 18 months, and replaced with 13vpcv in july 2011. since carriage surveillance can supplement ipd surveillance, we have monitored pneumococcal carriage in western australia (wa) since 2008 to assess the impact of the 10- ...201324349245
association between early bacterial carriage and otitis media in aboriginal and non-aboriginal children in a semi-arid area of western australia: a cohort study.streptococcus pneumoniae (pnc), nontypeable haemophilus influenzae (nthi) and moraxella catarrhalis (mcat) are the most important bacterial pathogens associated with otitis media (om). previous studies have suggested that early upper respiratory tract (urt) bacterial carriage may increase risk of subsequent om. we investigated associations between early onset of urt bacterial carriage and subsequent diagnosis of om in aboriginal and non-aboriginal children living in the kalgoorlie-boulder region ...201223256870
antibacterial antibody responses associated with the development of asthma in house dust mite-sensitised and non-sensitised children.backgroundinfants who develop house dust mite (hdm) allergy and hdm-sensitised children with severe persistent asthma have low antibody responses to the p6 antigen of haemophilus influenzae.objectiveto measure the development of antibody to two ubiquitous bacteria of the respiratory mucosa in a prospective birth cohort at high risk of allergic disease and to assess which responses are associated with asthma and atopy.methodsigg1 and igg4 antibody to h influenzae (p4 and p6) and streptoccocus pne ...201122106019
epidemiology of haemophilus influenzae bacteremia: a multi-national population-based assessment.haemophilus influenzae is an important cause of invasive infection but contemporary data in non-selected populations is limited.201021094183
community-acquired pneumonia in the central desert and north-western tropics of australia.community-acquired pneumonia (cap) results in significant morbidity in central and north-western australia. however, the nature, management and outcome of cap are poorly documented. the aim of the study was to describe cap in the kimberley and central desert regions of australia.201020561364
sentry antimicrobial surveillance program asia-pacific region and south africa.the sentry antimicrobial surveillance program was initiated in january 1997 and was designed to monitor the predominant pathogens and antimicrobial resistance for both nosocomial and community-acquired infections globally by using validated, reference-quality identification and susceptibility testing methods performed in a central laboratory. consecutive bacterial or fungal isolates, deemed clinically significant by local criteria, are forwarded to the local reference laboratory from various stu ...200312807276
australia's notifiable diseases status, 1996. annual report of the national notifiable diseases surveillance system.in 1996 there were 65,024 notifications to the national notifiable diseases surveillance system. the record high number of ross river virus infection notifications was of particular note. the highest rates were recorded in western australia, where an outbreak was documented in the south west, and in queensland. most cases occurred in the late summer and early autumn months. the number of measles cases has continued to fall markedly following the outbreak in 1993 and 1994. rubella notifications a ...19979339602
the burden of haemophilus influenzae type b disease in australia and an economic appraisal of the vaccine prp-omp.to estimate the incidence and sequelae of haemophilus influenzae type b disease (hib) in the australian population, and to evaluate the costs and outcomes of a vaccination program using the vaccine prp-omp at two, four and 12 months.19948170423
sequelae of haemophilus influenzae type b meningitis in aboriginal and non-aboriginal children under 5 years of age.between 1984 and 1990, 257 cases of haemophilus influenzae type b (hib) meningitis occurred in children under five years of age in western australia. we obtained information on possible sequelae in 131 cases (all non-aboriginal) by medical record review and parental interview, and in a further 116 cases (60 non-aboriginal, 56 aboriginal) by medical record review only; no follow-up information was available for ten children (nine non-aboriginal, 1 aboriginal). the incidence of hib meningitis in c ...19947833072
the epidemiology of acute epiglottitis in children in western australia.a comprehensive case definition was used to study all cases of epiglottitis that occurred in children under 15 years of age in western australia during a 5 year period. there was microbiological evidence of haemophilus influenzae type b infection in 71% of 103 cases of epiglottitis. seventy-five per cent of cases occurred in children under 5 years of age. in this age group, the estimated annual incidence (13.5 episodes per 100,000) was significantly lower than that reported in victoria (22.7 per ...19921466944
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