| [malaria situation in the people's republic of china in 2011]. | totally 4 479 malaria cases were reported through the annual reporting system from 782 counties of 27 provinces/ municipalities/autonomous regions (p/m/a) in 2011, this created a new-low number representing 43.0% reduction compared with 7 855 cases in 2010, and accordingly the annual incidence was reduced to 0.033 4/10 000. however, the number of malaria deaths increased to 33 from 19 in 2010. among the 782 counties with reported cases, 2 counties of motuo (16.466 0/10 000) in tibet and ruili (1 ... | 2012 | 23484249 |
| [malaria epidemic trend and characteristics at monitoring sites in yunnan province in 2008]. | malaria situation in 5 monitoring sites of yunnan showed a decline trend from 2005 to 2008. the average malaria incidence in 2008 was 11.84/10,000 with a decrease of 66.1% in comparison to 2005. the seropositive rate with immuno-fluorescence assay (ifa) was 4.61% for pupils. 82% of the cases chose town or township hospitals as the first place of seeking diagnosis and treatment. 83.6% cases were diagnosed over 3 days of symptom appearing. the main clinical manifestation was fever every other day ... | 2011 | 21823327 |
| [genotyping of plasmodium vivax in china-myanmar border by circumsporozoite protein]. | by using a series of type-specific primers for plasmodium vivax circumsporozoite protein (csp) gene and nested pcr, genotyping was conducted for the specimens of plasmodium vivax isolated from china-myanmar border. in 174 isolates of p. vivax, four genotypes, namely, tropical zone family strain, temperate zone family strain, genotype-mixed infection and pv-ii type, were identified each accounting for 54.6%, 35.6%, 6.9%, and 2.9%, respectively. the tropical zone family strain was dominant in the ... | 2010 | 21137309 |
| Genetic diversity of transmission-blocking vaccine candidates Pvs25 and Pvs28 in Plasmodium vivax isolates from Yunnan Province, China. | ABSTRACT: BACKGROUND: Transmission-blocking vaccines (TBVs) have been considered an important strategy for disrupting the malaria transmission cycle, especially for Plasmodium vivax malaria, which undergoes gametocytogenesis earlier during infection. Pvs25 and Pvs28 are transmission-blocking vaccine candidates for P. vivax malaria. Assessment of genetic diversity of the vaccine candidates will provide necessary information for predicting the performance of vaccines, which will guide us during t ... | 2011 | 22117620 |
| mekong malaria. ii. update of malaria, multi-drug resistance and economic development in the mekong region of southeast asia. | in an expansion of the first mekong malaria monograph published in 1999, this second monograph updates the malaria database in the countries comprising the mekong region of southeast asia. the update adds another 3 years' information to cover cumulative data from the 6 mekong countries (cambodia, china/yunnan, lao pdr, myanmar, thailand, viet nam) for the six-year period 1999-2001. the objective is to generate a more comprehensive regional perspective in what is a global epicenter of drug resist ... | 2003 | 15906747 |
| [a discussion on the csp genotyping of plasmodium vivax and malaria control in five southern provinces of china]. | to explore circumsporozoite protein (csp) genotype structure of plasmodium vivax in southern china and evaluate its epidemiological significance. | 2005 | 16562477 |
| space-time variation of malaria incidence in yunnan province, china. | understanding spatio-temporal variation in malaria incidence provides a basis for effective disease control planning and monitoring. | 2009 | 19646240 |
| spatio-temporal distribution of malaria in yunnan province, china. | the spatio-temporal distribution pattern of malaria in yunnan province, china was studied using a geographic information system technique. both descriptive and temporal scan statistics revealed seasonal fluctuation in malaria incidences in yunnan province with only one peak during 1995-2000, and two apparent peaks from 2001 to 2005. spatial autocorrelation analysis indicated that malaria incidence was not randomly distributed in the province. further analysis using spatial scan statistics discov ... | 2009 | 19706922 |
| use of pcr/dna probes to identify circumsporozoite genotype of plasmodium vivax in china. | the paper reports the result of identifying cirumsporozoite (cs) genotype of plasmodium vivax by using pcr/dna probe labeled with biotin. the sensitivity of this method to detect patient blood samples was 0.2 parasite/microl and also with high specific to p. vivax. cs genes from 52 blood samples collected from patients with p. vivax in hainan and yunnan provinces were amplified by pcr and 49 were positive by gel-e electrophoresis analysis, positive rate was 94%. then the amplified cs genes furth ... | 1999 | 10695781 |
| [epidemiologic survey of malaria at wei-xi county in yunnan province]. | | 1985 | 3912059 |
| [malaria situation in the people's republic of china in 1999]. | although the middle and lower reaches of changjiang river were consecutively stricken by severe flood in 1998 and 1999, the transmission of malaria was not frequent and prevalence of the disease was basically stable with no reports of outbreaks in the above areas, which was attributed to the intensification of malaria surveillance, prompt implementation of integrated measures including mosquito control and chemoprophylaxis, as well as the zoophilous trend of anopheles sinensis, the vector in the ... | 2000 | 12567683 |
| impact of climate variability on plasmodium vivax and plasmodium falciparum malaria in yunnan province, china. | malaria remains a public health problem in the remote and poor area of yunnan province, china. yunnan faces an increasing risk of imported malaria infections from mekong river neighboring countries. this study aimed to identify the high risk area of malaria transmission in yunnan province, and to estimate the effects of climatic variability on the transmission of plasmodium vivax and plasmodium falciparum in the identified area. | 2013 | 24341555 |
| clinical malaria along the china-myanmar border, yunnan province, china, january 2011-august 2012. | passive surveillance for malaria cases was conducted in yunnan province, china, along the china-myanmar border. infection with plasmodium vivax and p. falciparum protozoa accounted for 69% and 28% of the cases, respectively. most patients were adult men. cross-border travel into myanmar was a key risk factor for p. falciparum malaria in china. | 2014 | 24656298 |
| a molecular survey of febrile cases in malaria-endemic areas along china-myanmar border in yunnan province, people's republic of china. | imported malaria is a major threat to neighboring malaria-eliminating countries such as p.r. china and is difficult to monitor. a molecular survey of febrile patients with a history of traveling abroad along the myanmar-china endemic border areas from january 2008 to august 2012 was carried out. the rates of infection with species of plasmodium and compliance of microscopy diagnosis with nested pcr (polymerase chain reaction) results were calculated. | 2014 | 24954235 |
| molecular surveillance of pvdhfr, pvdhps, and pvmdr-1 mutations in plasmodium vivax isolates from yunnan and anhui provinces of china. | plasmodium vivax is the predominant species of human malaria parasites present in china. although sulphadoxine-pyrimethamine (sp) and chloroquine (cq) have been widely used for malaria treatment in china, the resistance profiles of these drugs are not available. analysis of dihydrofolate reductase (dhfr), dihydropteroate synthase (dhps), and multidrug resistance (mdr-1) gene mutations in p. vivax isolates is a valuable molecular approach for mapping resistance to sp and cq. this study investigat ... | 2014 | 25179752 |
| a household randomized, controlled trial of the efficacy of 0.03% transfluthrin coils alone and in combination with long-lasting insecticidal nets on the incidence of plasmodium falciparum and plasmodium vivax malaria in western yunnan province, china. | mosquito coils are the most commonly used household insecticidal product in the world with sales exceeding 50 billion coils, used by two billion people worldwide annually. despite strong evidence that coils prevent mosquito bites a systematic review concluded that there is no evidence that burning mosquito coils prevents malaria acquisition. therefore, the current trial was designed to measure and compare prevention of malaria infection by mosquito coils or long-lasting insecticidal net (llin) o ... | 2014 | 24885993 |
| risk assessment of malaria transmission at the border area of china and myanmar. | in order to achieve the goal of malaria elimination, the chinese government launched the national malaria elimination programme in 2010. however, as a result of increasing cross-border population movements, the risk of imported malaria cases still exists at the border areas of china, resulting in a potential threat of local transmission. the focus of this paper is to assess the plasmodium vivax incidences in tengchong, yunnan province, at the border areas of china and myanmar. | 2017 | 28679420 |
| microgeographic heterogeneity of border malaria during elimination phase, yunnan province, china, 2011-2013. | to identify township-level high-risk foci of malaria transmission in yunnan province, china, along the international border, we retrospectively reviewed data collected in hospitals and clinics of 58 townships in 4 counties during 2011-2013. we analyzed spatiotemporal distribution, especially hot spots of confirmed malaria, using geographic information systems and getis-ord gi*(d) cluster analysis. malaria incidence, transmission seasonality, and plasmodium vivax:p. falciparum ratio remained almo ... | 2016 | 27433877 |
| amplification of pfmdr1, pfcrt, pvmdr1, and k13 propeller polymorphisms associated with plasmodium falciparum and plasmodium vivax isolates from the china-myanmar border. | malaria in the china-myanmar border region is still severe; local transmission of both falciparum and vivax malaria persists, and there is a risk of geographically expanding antimalarial resistance. in this research, the pfmdr1, pfcrt, pvmdr1, and k13-propeller genotypes were determined in 26 plasmodium falciparum and 64 plasmodium vivax isolates from yingjiang county of yunnan province. the pfmdr1 (11.5%), pfcrt (34.6%), and pvmdr1 (3.1%) mutations were prevalent at the china-myanmar border. th ... | 2015 | 25691632 |
| transmission risk from imported plasmodium vivax malaria in the china-myanmar border region. | malaria importation and local vector susceptibility to imported plasmodium vivax infection are a continuing risk along the china-myanmar border. malaria transmission has been prevented in 3 border villages in tengchong county, yunnan province, china, by use of active fever surveillance, integrated vector control measures, and intensified surveillance and response. | 0 | 26401843 |
| mining geographic variations of plasmodium vivax for active surveillance: a case study in china. | geographic variations of an infectious disease characterize the spatial differentiation of disease incidences caused by various impact factors, such as environmental, demographic, and socioeconomic factors. some factors may directly determine the force of infection of the disease (namely, explicit factors), while many other factors may indirectly affect the number of disease incidences via certain unmeasurable processes (namely, implicit factors). in this study, the impact of heterogeneous facto ... | 2015 | 26013665 |
| monitoring plasmodium vivax chloroquine sensitivity along china-myanmar border of yunnan province, china during 2008-2013. | plasmodium vivax is the most widespread of the malaria parasites infecting human hosts. in malaria-eliminating settings, both imported and local malaria predominantly occurs in border areas, and most of them are p. vivax. chloroquine (cq) is the first-line drug for p. vivax treatment in china. to understand cq sensitivity in p. vivax, in vivo monitoring of cq resistance was conducted along the china-myanmar border from 2008 to 2013. | 2014 | 25224069 |
| plasmodium vivax malaria incidence over time and its association with temperature and rainfall in four counties of yunnan province, china. | transmission of plasmodium vivax malaria is dependent on vector availability, biting rates and parasite development. in turn, each of these is influenced by climatic conditions. correlations have previously been detected between seasonal rainfall, temperature and malaria incidence patterns in various settings. an understanding of seasonal patterns of malaria, and their weather drivers, can provide vital information for control and elimination activities. this research aimed to describe temporal ... | 2013 | 24350670 |
| artemisinin-naphthoquine combination versus chloroquine-primaquine to treat vivax malaria: an open-label randomized and non-inferiority trial in yunnan province, china. | plasmodium vivax is the main malaria parasite in china, and china is now making efforts to eliminate malaria by 2020. radical cure of vivax malaria is one of challenges for malaria elimination. the purpose is to evaluate the efficacy and safety of artemisinin-naphthoquine (anq) versus chloroquine-primaquine (cq-pq) in treatment of vivax malaria in yunnan province, china. | 2013 | 24215565 |
| assessment of therapeutic efficacy of chloroquine against falciparum malaria in an outbreak area in xishuangbanna, yunnan. | to investigate the failure of treatment with chloroquine in yunnan in order to help formulate adequate antimalarial drug policy. | 2002 | 12567568 |
| [investigation on genotype constitution of different plasmodium vivax isolates and its geographical distribution in china]. | to investigate the population constitution and geographical distribution of plasmodium vivax in china using molecular technique. | 2001 | 12572034 |
| [malaria surveillance in tengchong county of yunnan province in 2013]. | to analyze the surveillance data of malaria in tengchong county of yunnan province in 2013, so as to provide the evidence for carrying out the malaria elimination in the future. | 2015 | 26930941 |
| analysis of malaria epidemiological characteristics in the people's republic of china, 2004-2013. | this study aims to explore and characterize the malaria-endemic situation and trends from 2004 to 2013, to provide useful evidence for subsequently more effective strategic planning of malaria elimination in china. a total of 256,179 confirmed malaria cases were recorded in this period, and 86.8% of them were reported during 2004-2008. between 2004 and 2008, plasmodium vivax was the major species (72.2%) of malaria parasite. most cases (67.3%) were found in male, and mainly in the age group of 3 ... | 2015 | 26078326 |
| [survey on malaria epidemics in china-myanmar border area]. | the malaria epidemics in laza city of myanmar and yingjiang county in yunnan province of china in 2012 and 2013 was reviewed retrospectively, and a survey on malaria infection was conducted in residents in the border areas. a total of 179 malaria cases were reported in yingjiang county from 2012 to 2013, with an average annual incidence of 2.9 per 10,000. of the 179 cases, 77.7% were imported cases and 22.3% were local cases; 79.3% were infected with plasmodium vivax, 20.1% with p. falciparum, a ... | 2015 | 26672214 |
| [experimental studies on the biological characteristics of plasmodium vivax in south yunnan]. | | 1986 | 3533306 |
| the anopheles community and the role of anopheles minimus on malaria transmission on the china-myanmar border. | malaria around the china-myanmar border is a serious health problem in the countries of south-east asia. an. minimus is a principle malaria vector with a wide geographic distribution in this area. malaria is endemic along the boundary between yunnan province in china and the kachin state of myanmar where the local anopheles community (species composition) and the malaria transmission vectors have never been clarified. | 2013 | 24034528 |