Publications

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molecular epidemiological confirmation and circumstances of occurrence of sheep (s) strains of mycobacterium avium subsp. paratuberculosis in cases of paratuberculosis in cattle in australia and sheep and cattle in iceland.distinct strains of mycobacterium avium subsp. paratuberculosis with a tendency to segregate in either sheep, or cattle and other ruminants, have been described and are known as s and c strains, respectively. these strains can be distinguished by a polymorphism in the is1311 element and other dna-based methods. c strains are relatively easy to culture from tissues and faeces of animals with paratuberculosis but s strains are difficult to culture. a retrospective survey of archival formalin-fixed ...200111267791
specificity of absorbed elisa and agar gel immuno-diffusion tests for paratuberculosis in goats with observations about use of these tests in infected goats.to determine the specificity of serological tests that are currently used in veterinary diagnostic laboratories in australia for detection of mycobacterium avium subsp paratuberculosis infection in goats.200315084016
surgical method for biopsy of terminal ileum and mesenteric lymph node of sheep for detection of mycobacterium avium subsp paratuberculosis. 200415088979
effect of a test and control program for johne's disease in victorian beef herds 1992-2002.to report on progress in johne's disease (jd) control in infected beef herds participating in the victorian johne's disease test and control program (tcp).200415088984
intrauterine and transmammary transmission of mycobacterium avium subsp paratuberculosis in sheep.to investigate intrauterine infection of foetuses with mycobacterium avium subsp paratuberculosis and the presence of infection in mammary secretions of sheep.200415359967
financial modelling of the potential cost of ovine johne's disease and the benefit of vaccinating sheep flocks in southern new south wales.to develop an enterprise gross margin (gm) model that predicts the on-farm financial impact of ovine johne's disease (ojd) for various sheep enterprises in australia. in addition, to estimate the benefits and costs of control through the use of the gudair vaccination, including a breakeven point.200818826512
comparison of pre- and post-vaccination ovine johne's disease prevalence using a bayesian approach.this study was conducted to evaluate the effectiveness of gudairâ„¢ vaccine in decreasing the prevalence of shedding of mycobacterium avium subsp. paratuberculosis (map) in flocks of varying initial prevalence. thirty-seven self-replacing merino flocks from new south wales and victoria (australia) that had been vaccinating lambs with gudairâ„¢ for at least five years were enrolled in the study. these flocks had been tested prior to or at commencement of vaccination using pooled faecal culture, agar ...201323578910
environmental survival of mycobacterium avium subsp. paratuberculosis in different climatic zones of eastern australia.the duration of survival of both the s and c strains of mycobacterium avium subsp. paratuberculosis in feces was quantified in contrasting climatic zones of new south wales, australia, and detailed environmental temperature data were collected. known concentrations of s and c strains in feces placed on soil in polystyrene boxes were exposed to the environment with or without the provision of shade (70%) at bathurst, armidale, condobolin, and broken hill, and subsamples taken every 2 weeks were c ...201424463974
investigation and diagnosis of nontuberculous mycobacteriosis in a captive herd of aoudad (ammotragus lervia).an epizootic of nontuberculous mycobacteriosis occurred in a captive herd of aoudad (ammotragus lervia) over a period of 18 mo. each of the affected animals was subject to a thorough postmortem examination that included histopathology, tissue concentration and acid-fast staining, aerobic and anaerobic bacterial culture, mycobacterial culture, and real-time polymerase chain reaction specific for mycobacterium tuberculosis dna. histopathologic lesions consistent with pulmonary mycobacteriosis, inc ...200919569478
culture of pooled tissues for the detection of mycobacterium avium subsp paratuberculosis infection in individual sheep. 200315080490
isolation of mycobacterium avium subsp paratuberculosis from the semen of rams with clinical johne's disease. 200111789915
molecular epidemiology of mycobacterium avium subsp. paratuberculosis: is900 restriction fragment length polymorphism and is1311 polymorphism analyses of isolates from animals and a human in australia.the distribution and prevalence of strains of mycobacterium avium subsp. paratuberculosis were determined among sheep, cattle, and other species with johne's disease in australia. a total of 328 isolates were evaluated from numerous farms in new south wales, victoria, tasmania, and south australia, australia. restriction fragment length polymorphism (rflp) analysis of genomic dna using bsteii and an is900 probe and is1311 polymorphism analysis using pcr and restriction endonuclease analysis (pcr ...200010970365
ovine johne's disease. 19979404611
trends in incidence of aids illnesses in australia from 1983 to 1994: the australian aids cohort.to assess time trends in incidence of aids illnesses in australia, a retrospective cohort of people diagnosed with aids from january 1, 1983 to december 31, 1994 in three hiv medicine units in sydney, melbourne, and perth was established. data on initial and subsequent aids illnesses were available for 2580 aids cases, or 45% of australian aids notifications over the study period. males represented 97.2% of the cohort, and hiv exposure category was homosexual contact for 89.9%. subcohorts were f ...19979377123
sensitivity and specificity of pooled faecal culture and serology as flock-screening tests for detection of ovine paratuberculosis in australia.the flock-level sensitivity of pooled faecal culture and serological testing using agid for the detection of ovine johne's disease-infected flocks were estimated using non-gold-standard methods. the two tests were compared in an extensive field trial in 296 flocks in new south wales during 1998. in each flock, a sample of sheep was selected and tested for ovine johne's disease using both the agid and pooled faecal culture. the flock-specificity of pooled faecal culture also was estimated from re ...200211849717
non-tuberculous mycobacterial lymphadenitis.non-tuberculous mycobacterial lymphadenitis has been recognized since medieval times by an array of names. the condition is familiar to paediatricians and paediatric surgeons but it often is not recognized in its early stages. a paediatric surgeon's experience of the condition in newcastle over 30 years is reviewed.19968611130
a preliminary study of possible genetic influences on the susceptibility of sheep to johne's disease.to investigate possible genetic influences on susceptibility or resistance of sheep to johne's disease.200516035186
field evaluation of tracer sheep for the detection of early natural infection with mycobacterium avium subsp paratuberculosis.to determine whether tracer sheep could be used to detect s strain mycobacterium avium subsp paratuberculosis on pasture, and to provide further insight into the early stages of infection.200415354852
changing epidemiology of pulmonary nontuberculous mycobacteria infections.nontuberculous mycobacteria (ntm) disease is a notifiable condition in queensland, australia. mycobacterial isolates that require species identification are forwarded to the queensland mycobacterial reference laboratory, providing a central opportunity to capture statewide data on the epidemiology of ntm disease. we compared isolates obtained in 1999 and 2005 and used data from the queensland notification scheme to report the clinical relevance of these isolates. the incidence of notified cases ...201020875283
differentiation of australian isolates of mycobacterium paratuberculosis using pulsed-field gel electrophoresis.to examine strain variation amongst australian isolates of mycobacterium paratuberculosis.19979469224
cross species transmission of ovine johne's disease from sheep to cattle: an estimate of prevalence in exposed susceptible cattle.to determine the prevalence of infection of cattle with the sheep strain of mycobacterium avium subsp paratuberculosis at least two years after exposure at < 6 months old.200818363982
phagocytic efficiency of monocytes and macrophages obtained from sydney blood bank cohort members infected with an attenuated strain of hiv-1.defective function of monocyte-derived macrophages contributes to hiv-1 pathogenesis. we found that phagocytosis of the opportunistic pathogens mycobacterium avium complex and toxoplasma gondii was impaired in monocytes obtained from individuals infected with wild-type strains of hiv-1 but generally not in monocytes collected over a 6-year period from sydney blood bank cohort (sbbc) members infected with nef/long terminal repeats (ltr) region-defective strains of hiv-1. however, longitudinal ana ...200314657753
association of microsatellite polymorphisms with immune responses to a killed mycobacterium avium subsp. paratuberculosis vaccine in merino sheep.to study the association of polymorphisms at five microsatellite loci with immune responses to a killed mycobacterium avium subsp. paratuberculosis (map) vaccine.201020927174
nontuberculous mycobacterial infection in children: a prospective national study.the epidemiology and management of nontuberculous mycobacterial (ntm) infection in australian children is unknown.200919636280
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