a combination of two genetic markers is sufficient for restriction fragment length polymorphism typing of mycobacterium tuberculosis complex in areas with a high incidence of tuberculosis.the incidence of tuberculosis (tb) in madagascar is 150 cases per 100,000 people. because of this endemicity, we studied the genetic diversity of mycobacterium tuberculosis strains isolated in four big cities in 1994 to 1995 with the aim of monitoring tb transmission. isolates from 316 cases of pulmonary tb (ptm(+)) were typed by southern hybridization with genetic markers is6110 and dr. of the 316 ptm(+) strains, 66 (20.8%) had a single is6110 band and were differentiated by the dr marker into ...200111283082
[extra-pulmonary tuberculosis in antananarivo. principal localizations and biological diagnosis].we describe the state of extrapulmonary tuberculosis in the capital of antananarivo, a city of high endemicity for tuberculosis but very low endemicity for hiv infection. the laboratory of mycobacteria in the institut pasteur of madagascar had examined from august 94 to april 95, 543 pathological samples issued from 295 patients clinically suspected of extrapulmonary tuberculosis (64% male and 36% female). the diagnosis of tuberculosis was confirmed for 47.7% of the patients (141/295), using eit ...19958638985
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