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dengue virus type 2: replication and tropisms in orally infected aedes aegypti mosquitoes.to be transmitted by its mosquito vector, dengue virus (denv) must infect midgut epithelial cells, replicate and disseminate into the hemocoel, and finally infect the salivary glands, which is essential for transmission. the extrinsic incubation period (eip) is very relevant epidemiologically and is the time required from the ingestion of virus until it can be transmitted to the next vertebrate host. the eip is conditioned by the kinetics and tropisms of virus replication in its vector. here we ...200717263893
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