Publications

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adequacy of empirical antifungal therapy and effect on outcome among patients with invasive candida species infections.although inadequate antimicrobial therapy has been demonstrated in multiple studies to increase the risk for death in bacterial infections, few data investigating the effect of antifungal therapy on outcome of serious fungal disease are available. we sought to assess the adequacy of empirical therapy and its effect on mortality in invasive candida species infections.200717576697
intensive care unit-acquired urinary tract infections in a regional critical care system.few studies have evaluated urinary tract infections (utis) specifically acquired within intensive care units (icus), and the effect of such infections on patient outcome is unclear. the objectives of this study were to describe the occurrence, microbiology, and risk factors for acquiring utis in the icu and to determine whether these infections independently increase mortality.200515774051
epidemiology, treatment and outcome of candidemia: a five-year review at three canadian hospitals.to determine treatment regimens and epidemiological patterns in the occurrence of candidemia, a review of cases occurring from 1992 to 1996 in three large canadian hospitals, university of alberta hospital (uah) and royal alexandra hospital (rah), edmonton, and foothills medical center (fmc), calgary, was carried out. cases were detected by reviewing microbiology laboratory records. there were 202 cases in all (uah 104, fmc 70, rah 28). for the five study years the candidemia rate was 4.5/10 000 ...200212100528
incidence and risk factors for acquiring nosocomial urinary tract infection in the critically ill.a urinary tract infection (uti) is the most common hospital-acquired infection. however, the epidemiology of intensive care unit (icu)-acquired utis is not well defined. the objective of this study was to describe the incidence, risk factors, and clinical outcomes of icu-acquired utis.200212040549
trends and sources of nosocomial fungaemia.concurrent surveillance of blood culture isolates in a 1000-bed tertiary care hospital over a 7-year period from 1986 to 1993 identified 102 episodes of nosocomial fungaemia, representing 6.6% of all episodes of nosocomial bloodstream infections and 0.49/1000 admissions. no significant change in the frequency, rate, source or microbial aetiology of nosocomial fungaemia occurred over the 7-year period. candida albicans accounted for 74%, followed by candida (torulopsis) glabrata (8%), c. parapsil ...19947898515
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