Publications

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one year prospective survey of candida bloodstream infections in scotland.a 12 month survey of candidaemia in scotland, uk, in which every scottish hospital laboratory submitted all blood isolates of yeasts for identification, strain typing and susceptibility testing, provided 300 isolates from 242 patients, generating incidence data of 4.8 cases per 100,000 population per year and 5.9 cases per 100,000 acute occupied bed days; 27.9 % of cases occurred in intensive care units. more than half the patients with candidaemia had an underlying disease involving the abdomen ...200717644714
oral candidosis in the elderly in long term hospital care.a total of 137 patients in long term hospital care were interviewed and examined to determine the prevalence, nature and most important causes of oral candidosis in the hospitalized elderly. oral candidal infection as determined by the imprint culture technique was present in 47% of patients with a further 31% being carriers of candida. the prevalence of chronic atrophic candidosis in denture wearers was 38%, while 26% of all patients had angular cheilitis, 67% of which had an infective etiology ...19911900531
fungal antigens as a source of sensitization and respiratory disease in scottish maltworkers.mycological and serological studies were carried out as part of a survey of respiratory disease in scottish maltworkers. 70% of stained sputum smears from 574 workers showed the presence of higher plant cells and/or myclelia, and the spores of common environmental fungi. penicillium spp. (90%), rhizopus stolonifer (48%) and yeasts (53%) were the dominant fungi in 699 sputum cultures, and showed a similar proportional distribution in 327 samples of grain, malt, culms and dusts from fifty-six malt ...1977589785
superficial mycoses in the west of scotland.ringworm formed almost 70 per cent of all superficial mycoses diagnosed. the feet and nails were most frequently affected and a single species, trichophyton rubrum was responsible for the majority of infections that required specialist attention. scalp ringworm which, until the middle of this century, was the most common form of the disease now constitutes only 5 per cent of infections and the majority of these are caused by the zoophilic fungus microsporum canis. the anthropophilic dermatophyte ...19817313682
epidemiology of an outbreak of candida endophthalmitis in heroin addicts: identification of possible source of infection by biotyping.biotyping was employed to investigate possible sources of candida endophthalmitis in heroin addicts. isolates of candida albicans recovered from patients and from injection paraphernalia, including lemon juice diluent from lemon-shaped plastic containers, were biotyped. the predominant biotypes were 153, 15 3/7. similar biotypes were recovered from lemon, mouthwash, mouth swab and vitreous samples.19883050011
excess mortality, length of stay and cost attributable to candidaemia.there were 1967 reports of candida species isolated from blood specimens in 2007 in the uk (excluding scotland). such infections are particularly common in the intensive care unit (icu). the impact of candidaemia on mortality, length of stay (los) and cost in a uk hospital was examined.200919744519
epidemiology and management of candidaemia - a retrospective, multicentre study in five hospitals in the uk.candidaemia is associated with high mortality. despite the fact that candida species account for close to 10% of all nosocomial bloodstream infections, relatively few studies have investigated the management of candidaemia in hospitals. our objective was to find out how candidaemia is managed in hospitals. data relating to all episodes of candidaemia for the year 2008 were retrospectively collected in five centres in scotland and wales. a total of 96 candidaemic episodes were recorded in the yea ...201121615542
epidemiologic study by dna typing of a candida albicans outbreak in heroin addicts.the epidemiology of an outbreak of candida endophthalmitis in heroin addicts was studied by dna typing. although one biotype was prevalent, the 13 isolates of candida albicans from seven of the patients were placed into six separate groups by dna type. thus, the outbreak of candidiasis was not, as had been concluded from biotyping, due to a c. albicans strain of common origin.19911671573
biofilm formation is a risk factor for mortality in patients with candida albicans bloodstream infection-scotland, 2012-2013.bloodstream infections caused by candida species remain a significant cause of morbidity and mortality in hospitalized patients. biofilm formation by candida species is an important virulence factor for disease pathogenesis. a prospective analysis of patients with candida bloodstream infection (n = 217) in scotland (2012-2013) was performed to assess the risk factors associated with patient mortality, in particular the impact of biofilm formation. candida bloodstream isolates (n = 280) and clini ...201626432192
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