| vector-borne viral diseases in sweden--a short review. | ockelbo disease, caused by a sindbis-related virus transmitted to man by mosquitoes, was first described in the central part of sweden in the 1960s as clusters of patients with fever, arthralgia and rash. an average annual rate of 30 cases was recorded in the 1980s but no cases have been diagnosed during the last few years. nephropathia epidemica (ne) characterized by fever, abdominal pain and renal dysfunction has been known to cause considerable morbidity in sweden during the last 60 years but ... | 1996 | 8800805 |
| detection strategies of tick-borne encephalitis virus in swedish ixodes ricinus reveal evolutionary characteristics of emerging tick-borne flaviviruses. | the flaviviral tick-borne encephalitis virus (tbev) is a human pathogen having significant impact on public health. the geographical distribution of tbev and tbev-like viruses is increasing, which makes it important to characterise the natural virus populations. here we present four rt-pcr strategies designed for detection of broad types of tick-borne flaviviruses. sequence information on more than 32% of a tbev genome was generated from a small pool of ticks collected in the stockholm archipela ... | 2007 | 17277902 |
| high diagnostic yield by csf-pcr for entero- and herpes simplex viruses and tbev serology in adults with acute aseptic meningitis in stockholm. | acute aseptic meningitis (aam) affects 10-20/100,000 inhabitants per years in sweden. up to the beginning of the 1980s the diagnoses were made by virus isolation and/or determination of viral antibodies in serum. the development of pcr for detection of viruses in csf samples has increased the sensitivity and diagnostic efficiency considerably. we investigated the aetiology of aam and the diagnostic efficiency in an adult population in stockholm, using a limited first-line combination of microbio ... | 2008 | 18615360 |
| clinical manifestations and antibody prevalence of lyme borreliosis and tick-borne encephalitis in sweden: a study in five endemic areas close to stockholm. | five populations, including 903 individuals living in 5 different areas close to stockholm, were studied with regard to clinical manifestations and antibody prevalence of lyme borreliosis (lb) and tick-borne encephalitis (tbe). the study areas involved 4 groups of islands in the baltic sea and 1 island in lake mälaren. serum samples from each individual were tested for antibody activity to borrelia burgdorferi using a sonicated whole spirochete antigen in an elisa, and to tbe-virus (tbev) by eli ... | 1993 | 8284644 |
| epidemiological studies of lyme borreliosis and tick-borne encephalitis. | the hard tick ixodes ricinus, vector of borrelia burgdorferi and tbe virus (tbev), is most abundant in the southern and central parts of sweden. about 2000 cases of lyme borreliosis (lb) and 50-80 cases of tick-borne encephalitis (tbe) are estimated to occur in sweden annually. five populations, including 903 individuals living in five different areas close to stockholm where lb and tbe are endemic, were studied with regard to the clinical manifestations and antibody prevalence of lb and tbe. th ... | 1994 | 8047853 |
| prevalence of tick-borne encephalitis and lyme borreliosis in a defined swedish population. | sera from 346 individuals living on lisö, an area south of stockholm, endemic for tick-borne encephalitis (tbe) and lyme borreliosis, were tested for antibody activity to tbe-virus (tbev) and borrelia burgdorferi, using a sonicate antigen, by haemagglutination-inhibition and elisa, respectively. 10/346 (3%) individuals had a history of previous serologically confirmed tbe with encephalitic symptoms, and 33/346 (10%) had a history of previous erythema chronicum migrans (ecm). four individuals (1% ... | 1990 | 2371545 |
| epidemiology of tick-borne encephalitis in sweden 1956-1989: a study of 1116 cases. | tick-borne encephalitis (tbe) has occurred regularly in sweden since it was first diagnosed in 1954. in austria, where tbe is common, vaccination has been shown to reduce the incidence considerably. since this vaccine is now available in sweden we analysed 1116 cases of tbe from 1956 to october 1989 in order to define a strategy for vaccination. the cases were identified in the records from all infectious disease departments in sweden complemented with data from the virological laboratories. all ... | 1990 | 2371544 |
| tick borne encephalitis (tbe)-vaccination coverage and analysis of variables associated with vaccination, sweden. | to estimate the tick borne encephalitis (tbe)-vaccination coverage in the greater stockholm region, we sent a questionnaire to a randomized sample of 8000 individuals in 2013. fifty-three percent of all respondents (n=4307) reported being vaccinated against tbe at least once. reasons for not vaccinating included: no perceived risk (28.6%), too expensive (25.6%), did not have the time or opportunity (23%) and worried about vaccine side-effects (20.5%). multiple logistic regression revealed that t ... | 2015 | 26207593 |
| tick-borne encephalitis transmission risk: its dependence on host population dynamics and climate effects. | tick-borne encephalitis (tbe) is a human disease caused by a flavivirus that is spread by ticks (ixodes ricinus). in 2011 and 2012, the highest tbe incidence ever was recorded in sweden. it has been proposed that warmer spring temperatures result in higher survival of ticks and thus high incidence of tbe. here, analyses were done of time series of tbe for 1976-2011 in relation to the north atlantic oscillation (nao), mean summer temperatures, and yearly number of harvested european hare (lepus e ... | 2014 | 24745813 |
| childhood encephalitis in sweden: etiology, clinical presentation and outcome. | acute encephalitis is a relatively uncommon but potentially harmful cns inflammation usually caused by infection. the diagnosis is difficult to establish and the etiology often remains unclear. furthermore, the long-term prognosis of acute encephalitis in children is poorly described. in this study, we characterize childhood encephalitis from a swedish perspective in regard to etiology, clinical presentation and sequele. we retrospectively studied all children (n=93) who were admitted for acute ... | 2008 | 18313340 |
| antibody prevalence and clinical manifestations of lyme borreliosis and tick-borne encephalitis in swedish orienteers. | antibody prevalence and clinical manifestations of lyme borreliosis (lb) and tick-borne encephalitis (tbe) were studied in 362 orienteers from the county of stockholm during a large relay race in october 1990. from all participating orienteers, a blood sample was collected and a questionnaire completed. antibody activity to borrelia burgdorferi was measured using a sonicated whole spirochete antigen in an elisa, and to tbe virus (tbev) by elisa and haemagglutination inhibition (hi) test. a past ... | 1993 | 8284645 |
| a 10-year follow-up study of tick-borne encephalitis in the stockholm area and a review of the literature: need for a vaccination strategy. | 143 people treated for tick-borne encephalitis (tbe) were included in a retrospective follow-up study. sequelae and epidemiological characteristics in 114 individuals were analysed. the case fatality rate and the prevalence of residual paresis were low, 1.4 and 2.7%, respectively. however, 40 (35.7%) individuals were found to have a postencephalitic syndrome after a median follow-up time of 47 months, and a majority (77.5%) of these were classified as moderate to severe. various mental disorders ... | 1996 | 8863349 |