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lack of evidence of chlamydia pneumoniae infection in infants with acute lower respiratory tract disease.in order to determine whether there is serologic evidence of chlamydia pneumoniae infection in young infants with acute lower respiratory tract infection, serum samples from 86 subjects aged less than 6 months were assayed for igg and igm antibodies to chlamydia pneumoniae using a microimmunofluorescence method. infants hospitalized in toronto, canada, were enrolled between 15 march 1991 and 15 march 1992. no patient had infection determined by the serologic results. igg antibody was detected at ...19938112356
multiplex pcr for detection of chlamydia trachomatis and neisseria gonorrhoeae in genitourinary specimens.we developed a multiplex pcr (m-pcr) assay for the simultaneous detection of chlamydia trachomatis and neisseria gonorrhoeae. m-pcr employed c. trachomatis-specific primers kl1-kl2 and n. gonorrhoeae-specific primers ho1-ho3 and produced products of 241 and 390 bp, respectively. pcr products were easily detected by agarose gel electrophoresis and confirmed by southern hybridization using labelled oligonucleotide probes. m-pcr had a sensitivity of 10 fg of c. trachomatis and n. gonorrhoeae dna (e ...19958576375
detection of chlamydia trachomatis in genitourinary tract specimens using an automated enzyme-linked fluorescent immunoassay.the vidas enzyme linked fluorescent assay is a fully automated assay for the detection of chlamydia trachomatis in clinical specimens. because there is an increasing demand for automated assays for large volume laboratories and there is little performance data available, the authors evaluated the performance of the vidas enzyme linked fluorescent assay by comparing it with chlamydiazyme and polymerase chain reaction.19968919737
cost-effectiveness of screening swab or urine specimens for chlamydia trachomatis from young canadian women in ontario.undetected and untreated chlamydia trachomatis infections can result in a significant health burden. diagnostic testing refers to tests performed on patients with symptoms, whereas screening refers to testing specimens in asymptomatic patients. the goal of diagnostic testing and screening programs are early identification of infections to prevent upper tract infection and transmission to other partners.200111725225
screening guidelines for chlamydia trachomatis infection. evaluating physician awareness, agreement, and use.to assess whether physicians were aware of, agreed with, and followed the "1989 canadian guidelines for screening for chlamydia trachomatis infection "as they applied to screening asymptomatic women.19957734996
frequency of ocular chlamydial infection among young adults.young adults are at particular risk for chlamydia trachomatis infection. to determine whether there is a high rate of asymptomatic ocular chlamydial infection in this population, 131 eyes from 72 patients aged 18 to 30 years with no symptoms of conjunctivitis were tested for c. trachomatis by means of mccoy cell culture and a direct enzyme immunoassay. in addition, 51 of the patients underwent serologic testing to detect systemic chlamydial disease. ocular chlamydial infection was not found in a ...19921555129
detection of neisseria gonorrhoeae and chlamydia trachomatis in pharyngeal and rectal specimens using the bd probetec et system, the gen-probe aptima combo 2 assay and culture.this study compared the sensitivity and specificity of culture and two nucleic acid amplification tests (naats): the bd probetec et system (pt) and the aptima combo 2 (ac2) in detecting neisseria gonorrhoeae (gc) and chlamydia trachomatis (ct) in pharyngeal and rectal specimens.200919126571
high cost of chlamydia can be cut, researcher finds. 199910234330
effectiveness and efficiency of selective vs universal screening for chlamydial infection in sexually active young women.since chlamydial cervicitis is not associated with specific complaints, screening asymptomatic women is an important initiative to prevent pelvic inflammatory disease and its sequelae. compared with universal screening, selective screening is less costly but less effective so the cost savings vs the consequences of missing infected women need to be weighed carefully.19921520050
the effect of changes in cervical cancer screening guidelines on chlamydia testing.many chlamydia infections are identified through screening, which is frequently offered to females concomitantly with cervical cancer screening. recent cervical cancer screening guidelines recommend screening less frequently and starting later. we sought to evaluate the impact of the may 2012 ontario, canada, cervical cancer screening guideline change on papanicolaou (pap) and chlamydia trachomatis (chlamydia) testing and incidence.201728694268
the utility and cost of chlamydia trachomatis and neisseria gonorrhoeae screening of a male infertility population.objective: to determine the utility and cost of chlamydia trachomatis (ct) and neisseria gonorrhoeae (ng) screening in infertile males. design: cohort study. setting: canadian tertiary-level male infertility clinic and university-affiliated laboratories. patient(s): 5,588 male infertility patients. intervention(s): ct and ng testing on 8,972 urine and semen samples. main outcome measure(s): prevalence of ct and ng infection in infertile males versus general male population in canada over 8 years ...201122192351
prevalence of chlamydia trachomatis infections and specimen collection preference among women, using self-collected vaginal swabs in community settings.chlamydia trachomatis is a common, often asymptomatic sexually transmitted infection.200314646634
impact of urine collection order on the ability of assays to identify chlamydia trachomatis infections in men.noninvasive urine samples have been used to diagnose chlamydia trachomatis infections, with the assumption that the first-void urine (fvu), defined as the first 20 to 30 ml at any micturition, would be the optimal collection. we compared testing technologies on first, second, and third volumes for diagnosis.200312671557
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