Publications

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[prevalence and risk factors of chlamydia trachomatis infections in clients of a venereal disease outpatient clinic in amsterdam]. 19902304585
[prevalence and risk factors of chlamydia trachomatis infection in clients of a venereal disease clinic in amsterdam].we studied the prevalence of chlamydia trachomatis (ct) infection as well as its predictors among a sample (1000) of visitors (651 male, 349 female) of a clinic for sexually transmitted diseases (std) in amsterdam. the prevalence of ct was higher than that of gonorrhoea: among men, 14.3% and 11.5% and among women, 12.9% and 6.3% respectively. independent predictors for ct infections were for men: number of leucocytes in discharge or urine, nature of urethral discharge, age and sex behavior, and ...19892586677
[incidence of sexually transmissible disorders in clients of 2 ambulatory venereal disease clinics in amsterdam, 1981-1987].since 1981 sexually transmitted diseases (std) diagnosed at the std clinics of the municipal health service of amsterdam, are registered by sex, sexual orientation and prostitution. numbers of diagnoses per 1,000 new consultations are compared for each group of visitors over the period 1981-1987. among heterosexual visitors there has been a steady decline of gonorrhoea and trichomoniasis since 1981. genital herpes and venereal warts after increasing until 1985 have reached a plateau. because of ...19892725749
[the prevalence of chlamydia trachomatis infections in a general hospital in amsterdam]. 19873309684
sexually transmitted diseases reported by std services in the netherlands, 1984-1990.to present general trends in sexually transmitted disease (std) in the netherlands during the period 1984-1990 and to describe characteristics of the patients in order to get insight into possible factors underlying these trends.19938282295
hiv, sexually transmitted diseases and gynaecologic disorders in women: increased risk for genital herpes and warts among hiv-infected prostitutes in amsterdam.to determine the incidence of sexually transmitted diseases (std; gonorrhoea, early syphilis, chlamydia trachomatis infection, trichomoniasis and primary genital herpes) and gynaecologic disorders (vaginal candidiasis, anaerobic vaginosis, genital ulcerations of unknown cause, pelvic inflammatory disease, recurrent genital herpes, recurrent genital warts) in a cohort of hiv-infected and non-infected drug-using prostitutes in amsterdam between 1986 and 1992.19958527081
differences in the sensitivity of the amplicor chlamydia trachomatis pcr assay.to evaluate the use of the amplicor pcr assay in two european centres (amsterdam and vienna) as a standard for amplification assays in comparative studies.19979306903
[opportunistic screening for genital infections with chlamydia trachomatis in sexually active population of amsterdam. ii. cost-effectiveness analysis of screening women].to estimate the cost effectiveness of chlamydia trachomatis (ct) screening of young women visiting general practitioners.199910321301
[opportunistic screening for genital infections with chlamydia trachomatis in sexually active population of amsterdam. ii. cost-effectiveness analysis of screening women]. 199910368724
[systematic home screening for chlamydia trachomatis infections of asymptomatic men and women in family practice by means of mail-in urine samples].to determine the prevalence and determinants of chlamydia trachomatis (ct) infections among asymptomatic men and women in general practice. to determine participation rates in a systematic screening programme in general practice, using home obtained mailed urine samples.199910321300
[opportunistic screening for genital infections with chlamydia trachomatis among the sexually active population of amsterdam. il over 90% participation and almost 5% prevalence].to determine in an opportunistic screening programme for chlamydia trachomatis (ct) the participation and the ct prevalence among the heterosexual population.199910321299
[screening for chlamydia trachomatis infection: which group should be targeted and at what price?].this journal issue features three articles on screening in amsterdam, the netherlands, for infection with chlamydia trachomatis (ct): one on opportunistic screening (patients were invited to participate who consulted a general practitioner for other causes), one on the cost/benefit analysis of such screening, and one on systematic screening (all people registered in general practices were asked to mail a urine sample). the prevalence of ct infection was 8.7% in the opportunistic screening for al ...199910321294
[opportunistic screening for genital infections with chlamydia trachomatis among the sexually active population in amsterdam. iii. cost-effectiveness analysis of screening women and the role of reinfection and partner treatment].the role of reinfection and the importance of partner treatment were added to a pharmacoeconomic model for the analysis of a gp-based opportunistic screening programme for chlamydia trachomatis (ct) in sexually active women in amsterdam. a favourable cost-effectiveness was found for partner treatment. partner treatment was cost saving and overall net costs per major outcome averted by the screening programme were reduced by 40% or more due to partner treatment. from a pharmacoeconomic point of v ...199910590778
disappointing performance of literature-derived selective screening criteria for asymptomatic chlamydia trachomatis infection in an inner-city population.in an inner-city population with a low prevalence of chlamydia trachomatis infection, selective screening may be indicated to increase the efficiency of screening.200011034524
low diagnostic accuracy of selective screening criteria for asymptomatic chlamydia trachomatis infections in the general population.to develop and validate selective screening criteria for asymptomatic chlamydia trachomatis infections in the general population.200011141855
screening for chlamydia trachomatis; the amsterdam experience. 200011526697
comparison between the lcx probe system and the cobas amplicor system for detection of chlamydia trachomatis and neisseria gonorrhoeae infections in patients attending a clinic for treatment of sexually transmitted diseases in amsterdam, the netherlands.two assays for the detection of chlamydia trachomatis and neisseria gonorrhoeae were compared: the lcx probe system (the lcx system; abbott diagnostic laboratories, north chicago, ill.) and the cobas amplicor c. trachomatis/n. gonorrhoeae system (the cobas amplicor system; roche diagnostic systems, branchburg, n.j.). endocervical swab specimens, male urethral swab specimens, and female and male urine specimens were collected from 503 female and 498 male visitors attending a sexually transmitted ...200111230391
[increased incidence of gonorrhea and chlamydia trachomatis infections in family practice in southeast amsterdam, 1996-2000].to obtain insight into the incidence of gonorrhoea and chlamydia trachomatis infection (ct infection), and to identify any increase in these rates in a general practice in amsterdam, the netherlands.200111561487
cost-effectiveness of partner pharmacotherapy in screening women for asymptomatic infection with chlamydia trachomatis.to assess the cost-effectiveness of pharmacotherapy for male partners in screening women for asymptomatic infection with chlamydia trachomatis (ct).200111705188
[increased incidence in gonorrhea and chlamydia trachomatis infection in a general practice in amsterdam-zuidoost, 1996-2000]. 200211887629
new lymphogranuloma venereum chlamydia trachomatis variant, amsterdam.we retrospectively conducted a study of men who have sex with men who visited the amsterdam, the netherlands, sexually transmitted diseases clinic from january 2002 to december 2003 and had rectal chlamydia trachomatis infections. we found that symptomatic (73%) as well as asymptomatic (43%) patients were infected with a new c. trachomatis lgv variant.200516022786
slow epidemic of lymphogranuloma venereum l2b strain.we traced the chlamydia trachomatis l2b variant in amsterdam and san francisco. all recent lymphogranuloma venereum cases in amsterdam were caused by the l2b variant. this variant was also present in the 1980s in san francisco. thus, the current "outbreak" is most likely a slowly evolving epidemic.200516318741
prediction of chlamydia trachomatis infection: application of a scoring rule to other populations.active case finding is crucial to reduce transmission and consequences of chlamydia trachomatis (ct) infections. we previously proposed the use of a prediction rule for ct infection for selective screening of high-risk individuals in a population. to support such an application, the prediction rule needs to be validated in other populations.200616505746
no indication of swedish chlamydia trachomatis variant among sti clinic visitors in amsterdam. 200717370951
evaluation design of a systematic, selective, internet-based, chlamydia screening implementation in the netherlands, 2008-2010: implications of first results for the analysis.a selective, systematic, internet-based, chlamydia screening implementation for 16 to 29-year-old residents started in three regions in the netherlands in april 2008: in the cities of amsterdam and rotterdam and a more rural region, south limburg. this paper describes the evaluation design and discusses the implications of the findings from the first screening round for the analysis. the evaluation aims to determine the effects of screening on the population prevalence of chlamydia trachomatis a ...201020374635
rationale, design, and results of the first screening round of a comprehensive, register-based, chlamydia screening implementation programme in the netherlands.implementing chlamydia trachomatis screening in the netherlands has been a point of debate for several years. the national health council advised against implementing nationwide screening until additional data collected from a pilot project in 2003 suggested that screening by risk profiles could be effective. a continuous increase in infections recorded in the national surveillance database affirmed the need for a more active approach. here, we describe the rationale, design, and implementation ...201020925966
anal infections with concomitant chlamydia trachomatis genotypes among men who have sex with men in amsterdam, the netherlands.lymphogranuloma venereum (lgv) proctitis is caused by chlamydia trachomatis (ct) genotype l and is endemic among men who have sex with men (msm) in western society. genotype l infections need to be distinguished from non-lgv (genotypes a-k) ct infections since they require prolonged antibiotic treatment. for this purpose, an in-house developed pmph based lgv polymerase chain reaction (pcr) test is used at the amsterdam sti outpatient clinic. we investigated retrospectively the anal ct genotype d ...201121401939
evaluation of high-resolution typing methods for chlamydia trachomatis in samples from heterosexual couples.we aimed to compare conventional ompa typing of chlamydia trachomatis with multilocus sequence typing (mlst) and multilocus variable-number tandem-repeat (vntr) analysis (mlva). previously used mlst and mlva systems were compared to modified versions that used shorter target regions and nested pcr. heterosexual couples were selected from among persons with urogenital c. trachomatis infections visiting the sexually transmitted infection outpatient clinic in amsterdam, the netherlands. we identifi ...201121653758
overestimation of complication rates in evaluations of chlamydia trachomatis screening programmes--implications for cost-effectiveness analyses.cost-effectiveness analyses of screening programmes for asymptomatic chlamydia trachomatis infection suggest that screening at low prevalences in the population is cost-effective. however, the decision models in these studies are based on assumptions about the risk of complications, which are derived from the literature. incorrect assumptions may lead to under- or overestimation of the effectiveness of screening. the first objective of this paper is to evaluate the assumptions about the probabil ...200415082651
effectiveness and cost-effectiveness of a pharmacy-based screening programme for chlamydia trachomatis in a high-risk health centre population in amsterdam using mailed home-collected urine samples.in order to increase case-detection of chlamydia trachomatis (ct) in a multicultural, low-income and high-ct-prevalence neighbourhood, a novel approach was piloted in collaboration with the pharmacy of the health centre. during a two-year period, women aged 15-29 years who collected their contraceptives at the pharmacy were offered ct-test materials. home-collected urine could be mailed to the laboratory and the general practitioner received the results. nine percent of respondents were ct-posit ...200415601485
[inguinal lymphogranuloma venereum in a man having sex with men: perhaps an example of the missing link to explain the transmission of the recently identified anorectal epidemic].a 38-year-old man who had sex with men, presented at the outpatient department for sexually transmitted diseases in amsterdam with a painful, red, fluctuating swelling in the left groin and general discomfort. he had been sexually active in the population of men who have sex with men, in which an anorectal lymphogranuloma venereum (lgv) epidemic has recently been discovered. unlike other cases where there was anorectal involvement, this patient was the first case of lgv with the classical inguin ...200415636477
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