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pooling samples: the key to sensitive, specific and cost-effective genetic diagnosis of chlamydia trachomatis in low-resource countries.the aims of this study were to compare the performance characteristics and cost-effectiveness of pooling endocervical samples for screening and diagnosis of chlamydia trachomatis, and to investigate the prevalence of c. trachomatis infection in women in leningrad oblast, russia. a total of 1500 endocervical samples were tested individually and when pooled in groups of 5 and 10 samples, respectively. a previously evaluated in-house diagnostic polymerase chain reaction (pcr) assay was utilized. th ...200717340020
diagnosis of chlamydia trachomatis in russia--in-house pcr assays may be effective but overall optimization and quality assurance are urgently needed.in the present study, the performance of the cell culture method, two non-russian direct immunofluorescence (dif) assays, and three different in-house polymerase chain reaction (pcr) tests used in st. petersburg, russia, for detection of chlamydia trachomatis in urogenital specimens was evaluated. a total of 650 patients were examined and it was most disquieting that previous c. trachomatis positivity with russian dif assays could - 7 days later - be confirmed only in 26% of the women and 30% of ...200616907855
[respiratory chlamydial infection in children with a complicated course of acute respiratory viral infections].the role and influence of chlamydia trachomatis on the development and course of acute respiratory virus infections (arvi) in 130 children admitted to the hospital of the research institute of children's infections (st. petersburg) was studied. the occurrence of respiratory chlamydia infections in arvi patients with an unfavorable premorbid background was 35-36%. the disease took its course simultaneously with the mixed infection of the respiratory tract with viruses, pneumococci and their assoc ...19948017127
laboratory diagnostics for non-viral sexually transmitted infections in st. petersburg, russia: current situation and hallmarks for improvements.the numbers and performance characteristics of laboratories providing sexually transmitted infection (sti) diagnostic services, as well as the rates of morbidity due to stis in st. petersburg, russia, remain largely unknown.200818410333
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