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chlamydia trachomatis and human papillomavirus infection in indian women with sexually transmitted diseases and cervical precancerous and cancerous lesions.sexually transmitted diseases (stds) and anogenital cancers are the major health problems in indian women but no reliable estimate of the prevalence of either genital chlamydial infection or human papillomavirus (hpv) infection in std patients is available. the aim of this study was to detect the frequency of chlamydia trachomatis and the most prevalent high-risk hpv type 16 (hpv 16) infection in indian women, with stds and precancerous and cancerous lesions of the uterine cervix by polymerase c ...200011168078
prevalence of bacterial vaginosis among women in delhi, india.bacterial vaginosis is the most common cause of vaginal discharge among women in reproductive age. surveillance studies on bacterial vaginosis are mostly based on specialist clinic settings. as few population-based prevalence surveys of bacterial vaginosis have been conducted, we studied the prevalence of bacterial vaginosis in the urban and rural communities in delhi, and to associate the presence of bacterial vaginosis with demographic profile, risk factors and presence of other reproductive t ...200717431287
community-based study on seroprevalence of herpes simplex virus type 2 infection in new delhi.to determine the seroprevalence of herpes simplex virus type 2 (hsv-2) in two urban communities in delhi and to correlate the presence of hsv-2 seroprevalence with sociodemographic profile, risk factors and presence of other reproductive tract infections (rtis).200818227595
syndromic management of vaginal discharge among women in a reproductive health clinic in india.to examine the performance of the syndromic approach in the management of vaginal discharge among women attending a reproductive health clinic in new delhi, india.200011026889
screening for genital chlamydial infection in symptomatic women.during a two year period, the prevalence of genital chlamydial infection was assessed by papanicolaou and giemsa cytology of endocervical specimens from 396 women attending a gynaecology outpatient department in a delhi hospital, with symptoms of lower genital tract infection and primary or secondary infertility. the results of cytological examination were confirmed by isolation in a cell culture system. prevalence was found to be 41 per cent (93 of 227) in patients presenting with vaginal disch ...19938225447
seroprevalence of chlamydia trachomatis types in children with clinical trachoma in new delhi, india.micro-immunofluorescence test with type specific antigens of ocular chlamydial infection types a-d was used for serotyping the causative c. trachomatis serotypes in 32 inclusion positive school children suffering from trachoma. single serotype associated infection was seen in six of the patients. the rest of them had antibodies against more than one serotype indicating simultaneous or previous infection by more than one serotype. by geometric mean titre determination, type c appeared to be the m ...19911669643
chlamydia trachomatis elementary bodies in synovial fluid of patients with reactive arthritis and undifferentiated spondyloarthropathy in india.reportedly, there is little information on the magnitude of genitourinary-induced reactive arthritis (grea) from india. genital infection with chlamydia trachomatis is a major health problem in india because of its high prevalence; therefore, this study was conducted with the aim to screen rea/undifferentiated spondyloarthropathy (uspa) patients (n = 20) attending a major city hospital in new delhi, for investigating the presence of intra-articular chlamydial antigen in knee joints. patients wit ...201624712657
ocular chlamydia trachomatis infections in patients attending a tertiary eye care hospital in north india: a twelve year study.ocular infection with chlamydia trachomatis is a major public health problem in densely populated countries like india. the true prevalence of such infections is uncertain due to insufficient data available from india. the aim of this study was to do a retrospective analysis of c. trachomatis eye infections in patients attending the outpatient department of dr rajendra prasad centre for ophthalmic sciences, all india institute of medical sciences, new delhi, over a period of 12 years.201223391797
the role of a commercial enzyme immuno assay antigen detection system for diagnosis of c. trachomatis in genital swab samples.in the present pilot study, endocervical and urethral swabs collected from 100 patients attending sexually transmitted disease (std) clinics and regional centre for std in two referral hospitals in new delhi were analyzed by enzyme immune assay (eia), polymerase chain reaction (pcr) and direct fluorescent antibody (dfa) for detection of c. trachomatis. it was found that eia could detect a very low number of cases (3/100) as against dfa (11/100) and pcr (9/100). thus, in spite of the widespread a ...201122120804
prevalence of chlamydia infection among women visiting a gynaecology outpatient department: evaluation of an in-house pcr assay for detection of chlamydia trachomatis.screening women for chlamydia trachomatis infection in developing countries is highly desirable because of asymptomatic infection. the existing diagnostic methods in developing countries are not effective and their sensitivity fall below 45.0% which leads to further spread of infection. there is an urgent need for improved and cost effective diagnostic tests that will reduce the burden of sexually transmitted infections in the developing world.201020822551
predominance of chlamydia trachomatis serovars associated with urogenital infections in females in new delhi, india.screening for chlamydia trachomatis was done for 280 endocervical swab samples by pcr specific for endogenous plasmid. age dependency was seen in symptomatic patients, with a high chlamydial prevalence rate (28%) found in younger women. genotyping by restriction fragment length polymorphism analysis of omp1 pcr-positive samples showed serovars d, e, and f to be the most prevalent.200312791909
species specific chlamydiae antibodies in voluntary blood donors of delhi.different species of genus chlamydia have been associated with ocular, genitourinary and respiratory infections, and coronary artery disease. since the majority of these infections remain asymptomatic or subclinical, antibodies may be present in apparently healthy individuals, and the determination of species specific chlamydia antibodies in a healthy population may reflect exposure. we therefore screened the sera of healthy blood donors for species specific chlamydia antibodies by microimmunofl ...200112025256
burden of chlamydia trachomatis in india: a systematic literature review.chlamydia trachomatis (hereafter ct) is gram-negative, obligate intracellular pathogen. it causes the world's most common non-viral sexually transmitted disease. india is home to the world's greatest burden of infectious diseases, yet information on prevalence rates of ct is scarce. this article systematically reviews the literature for the prevalence rates and testing methods in india. a total of 27 studies were included. four main patients groups (symptomatic women, infertile women, pregnant w ...201728582495
differential expression of circulating th1/ th2/ th17 cytokines in serum of chlamydia trachomatis-infected women undergoing incomplete spontaneous abortion.the study aimed to elucidate role of th1/th2/th17 cytokines in the immunopathogenesis of spontaneous abortion in chlamydia trachomatis (ct)-positive first-trimester aborters. endometrial curettage tissue and serum were collected from 145 aborters (spontaneous abortion (sa) group, n = 85; recurrent miscarriage (rm) group, n = 60) and 120 controls attending department of obstetrics & gynecology at safdarjung hospital, new delhi (india). polymerase chain reaction was used to detect ct plasmid/momp, ...201728648621
seroprevalence of antibodies against chlamydia trachomatis inclusion membrane proteins b and c in infected symptomatic women.proteins in the inclusion membrane of chlamydia trachomatis (ct) have been anticipated to play pivotal roles in the molecular and cellular interactions between the pathogen and host. however, there is lack of data on host immunity with respect to antibody responses against chlamydial inclusion proteins.200919759474
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