| chronic virus infections supress atopy but not asthma in a set of children from a large latin american city: a cross-section study. | abstract: background: the prevalence of allergic diseases has increased over recent decades in affluent countries, but remains low in rural populations and some non-affluent countries. an explanation for these trends is that increased exposure to infections may provide protection against the development of allergy. in this work we investigated the association between exposure to viral infections in children living in urban brazil and the prevalence of atopy and asthma. methods: school age childr ... | 2011 | 21569568 |
| the high frequency of ebv infection in pediatric hodgkin lymphoma is related to the classical type in bahia, brazil. | pediatric hodgkin lymphoma (hl) occurring in developing regions is different from hl in industrialized countries due to the higher frequency of association with epstein-barr virus (ebv) infection. this infection is related to classical hl (chl) but is virtually absent in nodular lymphocyte predominant hl (nlphl). we studied the phenotype and the expression of ebv gene products in 90 pediatric cases by immunohistochemistry and in situ hybridization. ebv-positive tumor cells were found exclusively ... | 2006 | 16896892 |
| frequent expansion of epstein-barr virus (ebv) infected cells in germinal centres of tonsils from an area with a high incidence of ebv-associated lymphoma. | burkitt's lymphoma (bl) and hodgkin's disease (hd) occurring in developing regions are frequently associated with epstein-barr virus (ebv) infection and have a high incidence in childhood. recent genotyping studies indicate that the tumour cells of both neoplasms represent b cells that contain somatically mutated immunoglobulin heavy chain genes. this implies that the precursors of these neoplasms have participated in the germinal centre (gc) reaction. we therefore presumed that normal lymphoid ... | 1999 | 10398087 |
| expression of epstein-barr virus-gene products in burkitt's lymphoma in northeast brazil. | the epstein-barr virus (ebv) is consistently found in tumor cells of burkitt's lymphoma (bl) endemic in central africa and malaria is considered a pathogenic cofactor. in contrast, fewer than 20% of bl cases occurring in western countries are ebv-associated. we have investigated 54 bl cases from bahia, a tropical region of northeast brazil, for expression of ebv gene products by in situ hybridization and immunohistology and performed typing of the ebv by polymerase chain reaction. ten pediatric ... | 1996 | 8652843 |