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epstein-barr virus in diffuse large b-cell lymphoma in immunocompetent patients in japan is as low as in western countries.according to previous reports, the frequency of epstein-barr virus (ebv) positivity in diffuse large b-cell lymphoma is higher in east asia (approximately 9%) than in western countries. the presence of the ebv genome was examined in diffuse large b-cell lymphoma patients registered with the osaka lymphoma study group (olsg) in osaka, japan, situated in east asia. the ebv-positive rate was examined with in situ hybridization (ish) in 484 immunocompetent diffuse large b-cell lymphoma patients regi ...201121181929
non-hodgkin's lymphoma of waldeyer's ring as a manifestation of lymphoproliferative diseases associated with human t-cell leukemia virus type 1 in southwestern japan.adult t-cell leukemia/lymphoma (atl) usually presents with node- and/or cutaneous-based diseases, with a leukemic picture. it is not clear whether atl initially manifests with lesions in waldeyer's ring (wr) in an atl-endemic area. in the present study, we examined distributions of immunophenotypes and the presence of human t-cell leukemia virus type 1 (htlv-1) and epstein-barr virus (ebv) genomes in 62 cases of non-hodgkin's lymphoma (nhl) of wr (nhl-wr) from two areas of japan: osaka, an atl-n ...19979310958
the presence and subtype of epstein-barr virus in b and t cell lymphomas of the sino-nasal region from the osaka and okinawa districts of japan.association between epstein-barr virus (ebv) and human malignancies, including sino-nasal lymphoma (snl), has been suggested. ebv-associated malignancies have been reported to show distinct geographic distribution.19957637319
polymorphous lymphoproliferative disorder: a clinicopathological analysis.lymphoproliferative disorder (lpd) with polymorphous composition of proliferation (polymorphous lpd), containing large lymphoid cells together with small lymphocytes, plasma cells, macrophages, and/or eosinophils, is found in individuals with immunodeficiency conditions. clinicopathological findings in 19 cases of polymorphous lpd registered with the osaka lymphoma study group, osaka, japan, were analyzed; they represented 0.4% of the registered cases. in six cases, there was a history of rheuma ...201020111873
diffuse large b-cell lymphoma in the young in japan: a study by the osaka lymphoma study group.clinicopathological and immunophenotypical characteristics in 24 patients with diffuse large b-cell lymphoma (dlbcl) under 30 years of age in osaka, japan were examined, and the results compared to those of dlbcl patients aged over 40 years in osaka and of young dlbcl patients in western countries. the level of ldh and ipi score at initial diagnosis were significantly lower in young than older patients. the sex ratio (m:f) and age range (median) in the young and older groups were 1.18 and 11-30 ...200717573693
nk-cell related neoplasms in osaka, japan.the frequency of nk-cell related neoplasms was estimated among lymphoproliferative diseases diagnosed and treated in osaka, japan, from 1999 to 2003. the total number of registered cases was 1,400, among which 1,092 patients were diagnosed as having malignant lymphomas. there were 987 cases of non-hodgkin's lymphoma (nhl) and 105 (9.6%) of hodgkin's lymphoma. immunophenotypic analysis revealed that 743 patients had b-cell lymphomas and 209 t/nk-cell lymphomas. among the t/nk-cell lymphomas, 40 s ...200415224357
epstein-barr virus in gastric carcinoma in suzhou, china and osaka, japan: association with clinico-pathologic factors and hla-subtype.information on geographic differences of epstein-barr virus (ebv) positivity and association with hla in gastric carcinoma are limited. therefore, the association of gastric carcinoma with ebv was examined in 118 patients from suzhou, china, where the incidence of nasopharyngeal carcinoma (npc) is high, and in 216 patients from osaka, japan, where the incidence of npc is low, npc being one of the ebv-associated carcinomas. expression of hla-a2 was also examined in some of these cases. the ebv ge ...19979139835
titers of epstein-barr virus-related antibodies in nasopharyngeal carcinoma in japan.it is thought that nonkeratinizing or undifferentiated squamous cell carcinoma in the nasopharynx (npc) is intimately correlated with epstein-barr virus (ebv). twenty-one patients with npc were followed in kyoto university hospital and 4 in osaka red cross hospital during the past 2 years from 1980 to 1981. these patients were classified histopathologically according to the who classification in 1978 and staged with the tnm classification in union internationale contre le cancer (uicc) in 1978. ...19846318948
plasmacytoma of the gastrointestinal tract in korea: higher incidence than in japan and epstein-barr virus association.as a result of a systematic review of non-hodgkin's lymphoma of the gastrointestinal tract (gi) at the yonsei university, seoul, korea and the osaka university, osaka, japan, we found an extramedullary plasmacytoma in 5 of a total of 78 cases (6.4%) in korea and 1 of 136 cases (0.7%) in osaka, which represents an approximately 9-fold difference in frequency. the presence of the epstein-barr virus (ebv) genome was examined in paraffin-embedded specimens from the 5 cases with gi plasmacytoma from ...19989428372
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