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[chronic fatigue syndrome--study of 51 cases treated at the second tokyo national hospital].fifty-one patients with chronic fatigue syndrome (cfs) were studied. tender points, which are a characteristic clinical feature of fibromyalgia, were found in all but two of the patients at 11.4 points (mean) per patient. igg antibody titers to eb virus viral capsid antigen were more elevated in the cfs patient group compared to that of the control (p < 0.0015). igg antibody titers to hhv-6 were not higher in the patient group. nk cell activity was not more decreased in the patient group, wherea ...19921337560
malignant lymphomas in japanese aids patients.seven non-hodgkin's malignant lymphomas (mls) were found in 25 japanese aids (acquired immune deficiency syndrome) patients who died at two hospitals in tokyo. all of these mls originated from extranodal organs including the brain (three cases), skin (two cases) liver and adrenal gland. b cell markers were demonstrated in all of them. epstein-barr virus (ebv) capsid antigen (ebvca) was demonstrated in 5/7, nuclear antigen (ebna) in 2/2, the w fragment of ebv dna by in situ hybridization in 5/7 a ...19911667449
marked decrease in the epstein-barr virus positivity rate in nodular sclerosis subtype hodgkin's disease in tokyo: trend between 1955 and 1999.we studied the trends of the epstein-barr virus (ebv) positivity rate in hodgkin's disease (hd) between 1955 and 1999. the overall positivity rate gradually decreased over time [12 out of 23 (52%) in 1955-69; 18 out of 39 (46%) in 1970-84; 13 out of 44 (35%) in 1985-99; p = 0.135]. interestingly, a marked decrease in the rate was noted in the nodular sclerosis (ns) subtype [5 out of 11 (45%); 4 out of 19 (21%); 1 out of 24 (4%); p < 0.01] but not in other classic hd [7 out of 11 (63%); 14 out of ...200111380410
prevalence of epstein-barr virus in japan: trends and future prediction.epstein-barr virus (ebv) is the causative agent of infectious mononucleosis and some malignancies including ebv-associated-lymphomas. a large portion of adults all over the world are infected with ebv. in children, however, there are geographic variations. most of the children in asia and in other developing countries are infected in their early life, before 1 year of age (>90% of 5-9-year-old children are infected), while the age of primary infection is delayed in western countries (approx. 50% ...200616497243
decrease in epstein-barr virus-positive aids-related lymphoma in the era of highly active antiretroviral therapy.recent introduction of highly active antiretroviral therapy (haart) is reported to have reduced the incidence of lymphoma among hiv-infected individuals. a clinicopathological study was performed on 86 aids-related lymphoma patients who were treated in tokyo area from 1987 to 2005. the incidence of lymphoma detected by autopsy was 27% (53 cases/198 autopsies). diffuse large b cell lymphoma was the most predominant histological subtype throughout the period (78%). burkitt's lymphoma (bl) increase ...200616697236
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