Publications

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antibiotic susceptibility of neisseria gonorrhoeae in trinidad and tobago.treatment failures with standard doses of penicillin have been observed in the sexually transmitted diseases (std) clinics in trinidad and tobago. in the absence of an ongoing surveillance system, the antimicrobial susceptibility of 518 neisseria gonorrhoeae strains was determined in order to guide treatment. 39 (7.6%) strains were resistant to penicillin, including 27 (5.2%) positive for beta-lactamase; that is penicillinase-producing neisseria gonorrhoeae (ppng). 51 (10%) strains were resistan ...19979494404
antimicrobial susceptibility of neisseria gonorrhoeae isolates from three caribbean countries: trinidad, guyana, and st. vincent.the percentage of neisseria gonorrhoeae isolates resistant to antimicrobial agents commonly used for treatment is unknown in many caribbean countries.200111518867
single dose (direct observed) azithromycin therapy for neisseria gonorrhoeae and chlamydia trachomatis in std clinic attenders with genital discharge in trinidad and tobago.the purpose of this study was to determine the prevalence and to assess the efficacy of a single one gram oral dose of azithromycin under direct observed therapy of genital discharge due to neisseria gonorrhoeae and chlamydia trachomatis infections in std clinic attenders in trinidad and tobago. all patients with genital discharge and their contacts were given one gram oral dose of azithromycin under direct supervision after collection of urethral and cervical swabs for n gonorrhoeae culture and ...200111769023
antibiotic resistant n. gonorrhoeae in trinidad and tobago.we tested the susceptibility patterns of 128 n. gonorrhoeae isolates to six antimicrobials; penicillin, tetracycline, spectinomycin, ceftriaxone, ciprofloxacin and azithromycin, and examined whether certain demographic or behavioral factors related to antibiotic use increased the likelihood of infection by a resistant strain. there was a low rate of resistance to penicillin; penicillinase-producing and chromosomal-mediated penicillin resistant gonorrhea were estimated to be 0.8%. a much higher p ...200111785665
determinants of gonorrhoea infection among std clinic attenders in trinidad--i: sociodemographic factors, knowledge, risk perception and history of std.we determined the prevalence of neisseria gonorrhoeae and describe sociodemographic factors, knowledge and sexually transmitted disease (std) history associated with gonococcal infection among 991 std clinic attenders in trinidad, west indies (wi). the prevalence of gonorrhoea was 25%. predictors for gonorrhoea were: male gender (odds ratios [or] 3.5), age 15-19 (or 2.5) and 20-29 years (or 2.1), unawareness of the term std (or 1.5), self-perceived risk for stds (or 1.7) and no history of syphil ...200211802929
determinants of gonorrhoea infection among std clinic attenders in trinidad--ii: sexual behavioural factors.sexual behavioural factors associated with gonococcal infection among 991 std clinic attenders in trinidad, west indies (wi) were determined by univariate and stepwise multiple logistic regression analysis. casual sex (odds ratios [or] 1.6) was the only predictor of gonorrhoea. among males, significant associations were identified by univariate analysis between concurrent partnerships, > or =one sexual partner(s) in the past 6 months, and drug use prior to engaging in casual and/or oral sex. no ...200211802930
in-house polymerase chain reaction for affordable and sustainable chlamydia trachomatis detection in trinidad and tobago.to provide a preliminary assessment of in-house polymerase chain reaction (pcr) as an alternative to the more costly commercial test for detection of asymptomatic infection by chlamydia trachomatis and to provide much needed demographic data on infection indicators within the trinidad and tobago public health care system.200718198040
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