| behavioral and socioeconomic risk factors associated with probable resistance to ceftriaxone and resistance to penicillin and tetracycline in neisseria gonorrhoeae in shanghai. | globally, incidence of neisseria gonorrhoeae infection is once again the highest of the bacterial sexually transmitted infections. the bacterium can produce serious complications in those infected, and emerging resistance to third generation cephalosporins could usher in an era of potentially untreatable gonorrhea. this research aimed to identify risk factors for antibiotic resistant gonorrhea infection among clients at a shanghai sexually transmitted infection clinic over two time periods, 2004 ... | 2014 | 24586792 |
| analysis of mutations in multiple loci of neisseria gonorrhoeae isolates reveals effects of pib, pbp2 and mtrr on reduced susceptibility to ceftriaxone. | to elucidate loci in neisseria gonorrhoeae implicated in reduced susceptibility to ceftriaxone. | 2011 | 21393127 |
| fluoroquinolone resistance among neisseria gonorrhoeae isolates from shanghai, china: detection of quinolone resistance-determining region mutations. | fluoroquinolone has a broad spectrum of antimicrobial activity, and is widely used for gonorrhoea treatment. however, its efficacy can be compromised by the drug-resistance property of neisseria gonorrhoeae isolates. most resistant cases of n. gonorrhoeae are associated with mutations in the quinolone-resistance-determining-region (qrdr) within genes of gyra and parc. this study was undertaken to describe resistance profile of n. gonorrhoeae to fluoroquinolones in shanghai, p.r. of china, and al ... | 2009 | 19692753 |
| fluoroquinolone resistance and mutation patterns in gyra and parc genes in neisseria gonorrhoeae isolates from shanghai, china. | in order to study the resistance of neisseria (n.) gonorrhoeae to the fluoroquinolone and detect mutation patterns of quinolone resistance-determining regions (qrdrs) of clinical isolates in shanghai, china, a total of 80 clinical isolates of n. gonorrhoeae were consecutively collected from shanghai. the mic of fluoroquinolone for the isolates was examined by using the agar dilution method and the mutation profiles of the qrdrs of gyra and parc were analyzed by sequencing and restriction fragmen ... | 2009 | 19224158 |
| clusters of circulating neisseria gonorrhoeae strains and association with antimicrobial resistance in shanghai. | (i) to distinguish neisseria gonorrhoeae isolates in shanghai by porb typing; (ii) to ascertain the congruence of porb dna sequence typing with cases linked epidemiologically; (iii) to determine the association of specific porb mutations with antimicrobial resistance to penicillin or tetracycline. | 2008 | 18227091 |
| antimicrobial susceptibility and molecular determinants of quinolone resistance in neisseria gonorrhoeae isolates from shanghai. | to determine the antimicrobial susceptibility of neisseria gonorrhoeae from shanghai and to type the quinolone resistance-determining regions (qrdrs) of ciprofloxacin-resistant isolates. | 2006 | 16880174 |
| twenty-five-year changing pattern of gonococcal antimicrobial susceptibility in shanghai: surveillance and its impact on treatment guidelines. | antimicrobial resistance of neisseria gonorrhoeae is a serious health problem in china. gonococcal antimicrobial susceptibility has been monitored in shanghai since 1988. in this study, we examined the changing pattern of gonococcal antimicrobial susceptibility based on data from n. gonorrhoeae isolates collected over the past 25 years. | 2014 | 25547132 |
| population dynamics of neisseria gonorrhoeae in shanghai, china: a comparative study. | gonorrhea is a major sexually transmitted disease (std) in many countries worldwide. the emergence of fluoroquinolone resistance has complicated efforts to control and treat this disease. we report the first study of the evolutionary processes acting on transmission dynamics of a resistant gonococcal population from shanghai, china. we compare these findings with our previous study of the evolution of a fluoroquinolone sensitive gonococcal population from baltimore, md. | 2010 | 20092631 |
| survey on antibiotic sensitivity of neisseria gonorrhoeae strains isolated in china, 1987-1992. | the appearance and the endemic of penicillinase-producing neisseria gonorrhoeae (ppng) and other resistant strains cause much difficulty in the treatment of gonorrhea. to keep surveillance of the strains is important for the control of gonorrhea nationwide. | 1994 | 7974078 |
| [correspondence analysis on random amplified polymorphic dna genotyping and drug-resistance of neisseria gonorrhoeae strains in pudong area, shanghai]. | using molecular epidemiology methods to investigate relationship between genotypes and drug-resistance of neisseria (n.) gonorrhoeae in shanghai area. | 2005 | 15921613 |
| in vitro activities of tigecycline against clinical isolates from shanghai, china. | to evaluate the in vitro activity of tigecycline, the minimum inhibitory concentrations (mics) of tigecycline against 1,201 strains of recent clinical isolates from 10 hospitals in shanghai, china were determined and compared with selected comparators. results showed that tigecycline had broad-spectrum antimicrobial activity. it was highly active against gram-positive cocci, including methicillin-resistant staphylococcus spp., penicillin-intermediate streptococcus pneumoniae, enterococcus faecal ... | 2004 | 15582300 |