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foodborne botulism in canada, 1985-2005.during 1985-2005, a total of 91 laboratory-confirmed outbreaks of foodborne botulism occurred in canada; these outbreaks involved 205 cases and 11 deaths. of the outbreaks, 75 (86.2%) were caused by clostridium botulinum type e, followed by types a (7, 8.1%) and b (5, 5.7%). approximately 85% of the outbreaks occurred in alaska native communities, particularly the inuit of nunavik in northern quebec and the first nations population of the pacific coast of british columbia. these populations were ...201323735780
activation phenomenon of clostridium botulinum type e toxin.gerwing, julia (the university of british columbia, vancouver, canada), claude e. dolman, and david a. arnott. activation phenomenon of clostridium botulinum type e toxin. j. bacteriol. 84:302-306. 1962-highly purified preparations of both nonactivated and trypsin-activated type e botulinus toxins have been analyzed in an ultracentrifuge. untreated botulinus type e toxin was found to have a sedimentation constant (s(20,w)) of 5.6 svedberg units, whereas trypsin-activated toxins would not form a ...196213898102
food-borne botulism in canada, 1971-84.sixty-one outbreaks of food-borne botulism involving a total of 122 cases, of which 21 were fatal, were recorded from 1971 to 1984 in canada. most occurred in northern quebec, the northwest territories or british columbia. of the 122 victims 113 were native people, mostly inuit. most of the outbreaks (59%) were caused by raw, parboiled or "fermented" meats from marine mammals; fermented salmon eggs or fish accounted for 23% of the outbreaks. three outbreaks were attributed to home-preserved food ...19852866023
purification and molecular weight determination of clostridium botulinum type e toxin.gerwing, julia (the university of british columbia, vancouver, british columbia, canada), claude e. dolman, m. e. reichmann, and hardial s. bains. purification and molecular weight determination of clostridium botulinum type e toxin. j. bacteriol. 88:216-219. 1964.-a method was developed whereby type e botulinus toxin can be obtained in a highly purified state by elution through acidified diethylaminoethyl-cellulose columns. the material thus isolated appears to be electrophoretically and ultrac ...196414197891
mechanism of tryptic activation of clostridium botulinum type e toxin.gerwing, julia (university of british columbia, vancouver, b.c., canada), claude e. dolman, and arthur ko. mechanism of tryptic activation of clostridium botulinum type e toxin. j. bacteriol. 89:1176-1179. 1965.-the toxic peptide of trypsin activated clostridium botulinum type e toxin was purified by chromatography through columns packed with sephadex g-75 and g-50. the molecular weight of the active peptide was estimated to lie between 10,000 and 12,000. amino acid analyses indicated that the a ...196514292982
isolation and characterization of a toxic moiety of low molecular weight from clostridium botulinum type a.gerwing, julia (the university of british columbia, vancouver, b.c., canada), claude e. dolman, and hardial s. bains. isolation and characterization of a toxic moiety of low molecular weight from clostridium botulinum type a. j. bacteriol. 89:1383-1386. 1965.-a toxic moiety of low molecular weight has been isolated from a type a strain of clostridium botulinum, by a method involving ammonium sulfate precipitation and elution through diethylaminoethyl cellulose at ph 5.6. by means of electrophore ...196514293025
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