Publications

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is there an association between ocular adnexal lymphoma and infection with chlamydia psittaci? the university of rochester experience.various subsets of extranodal marginal zone lymphomas of mucosa-associated lymphoid tissues (malt lymphomas) have been associated with infectious organisms. most notable of these is the association of gastric malt lymphomas with helicobacter pylori infection. in a recent publication ferreri et al. [ferreri aj, guidoboni m, ponzoni m, de conciliis c, dell'oro s, fleischhauer k, et al. evidence for an association between chlamydia psittaci and ocular adnexal lymphomas. j natl cancer inst 2004;96:5 ...200616246419
h. pylori infection and genotyping in patients undergoing upper endoscopy at inner city hospitals.kings county hospital (kch), and st. john's episcopal hospital (sjh) are inner-city hospitals in new york city serving predominantly minority populations. staten island university hospital (siuh) serves a predominantly middle-class caucasian population. we examined h. pylori (hp) infection in patients undergoing upper endoscopy at these hospitals. two gastric biopsies were obtained from each patient. one biopsy was examined by histology or the rapid urease test for the presence of hp. the other ...200212141819
hospital admissions for peptic ulcer and indigestion in london and new york in the 19th and early 20th centuries.the occurrence of peptic ulcer increased rapidly in all western countries from the 19th to the 20th century, attributed to a possible epidemic of helicobacter pylori, a new pathogenic strain, or a change in host susceptibility. the early trends in hospital admissions for peptic ulcer and dyspepsia in london and new york during the 19th century are reviewed to test these hypotheses.200211889081
period- and cohort-age contours of deaths from gastric and duodenal ulcer in new york 1804-1998.mortality data of peptic ulcer are mostly national and limited to the 20th century. the new york city data from 1804 have therefore been examined by both year of death and year of birth (cohort analysis), to consider whether the increases and subsequent decreases in deaths from gastric, followed by duodenal ulcer, can be attributed to helicobacter pylori.200111693322
the pharmacoeconomic impact of antimicrobial therapy for peptic ulcer disease in a large urban jail.to determine the pharmacoeconomic impact of antimicrobial treatment of peptic ulcer disease (pud) in a large urban jail.19989854250
prevalence of helicobacter pylori in peptic ulcer patients in greater rochester, ny: is empirical triple therapy justified?among patients with peptic ulcer disease, the prevalence of helicobacter pylori has been reported to range from 80% to 90%. thus empirical cost-effective therapy has been suggested. we surveyed patients with peptic ulcer disease in rochester, ny.19989576450
helicobacter pylori infection is associated with a high incidence of intestinal metaplasia in the gastric mucosa of patients at inner-city hospitals in new york.gastric carcinogenesis is a multistep process progressing from chronic gastritis, through glandular atrophy (ga), intestinal metaplasia (im) and dysplasia. infection of the stomach with h. pylori increases the risk of developing gastric cancer. few studies have examined the degree to which hp-induced changes occur in specific populations. in the present study, we examined the association between hp infection and histological changes in the gastric mucosa of patients at two inner-city hospitals i ...200616944298
acceptance of repeat esophagogastroduodenoscopy to detect gastric cancer in a chinese immigrant cohort.to study the feasibility of using repeat esophagogastroduodenoscopy (egd) to screen for helicobacter pylori infection and gastric cancer in an asian immigrant cohort.200616917402
seroprevalence of helicobacter pylori in new york city populations originating in east asia.helicobacter pylori prevalence is higher in developing countries than in industrialized countries, and within the latter, higher among immigrants than among nativeborn residents. using a point-prevalence survey, we sought to identify risk factors for h. pylori seropositivity in us urban east asian-born populations. at a clinic in new york city, we consecutively enrolled 194 east asian-born adults, who then responded to a survey and provided a blood sample. assays were performed to detect igg ant ...200516033932
association of polymorphisms in myeloperoxidase and catalase genes with precancerous changes in the gastric mucosa of patients at inner-city hospitals in new york.gastric carcinogenesis is a multistep process progressing from chronic gastritis, through glandular atrophy (ga), intestinal metaplasia (im) and dysplasia. we have previously demonstrated that minority patients at new york city hospitals are infected with a relatively virulent strain of h. pylori (hp) and that hp infection is associated with an increased incidence of precancerous changes in the gastric mucosa. nevertheless, precancerous changes are not observed in every hp-infected individual, s ...200717549373
follow-up care after a diagnosis of helicobacter pylori infection in an asian immigrant cohort.to study the rate at which helicobacter pylori infection is treated in an immigrant cohort after diagnosis by esophagogastroduodenoscopy (egd).200616340630
rising trends of gastric cancer and peptic ulcer in the 19th century.the risk of dying from gastric cancer appears to have increased among consecutive generations born during the 19th century. aim: to follow the time trends of hospitalization for gastric cancer and test whether they confirm such increase.201020659282
identification of helicobacter spp. in bile and gallbladder tissue of patients with symptomatic gallbladder disease.this experimental study was designed to determine if helicobacter spp. contribute to benign gallbladder disease using polymerase chain reaction (pcr) methods.201020495657
infectious burden and carotid plaque thickness: the northern manhattan study.the overall burden of prior infections may contribute to atherosclerosis and stroke risk. we hypothesized that serological evidence of common infections would be associated with carotid plaque thickness in a multiethnic cohort.201020075350
infectious burden and risk of stroke: the northern manhattan study.to determine the association between a composite measure of serological test results for common infections (chlamydia pneumoniae, helicobacter pylori, cytomegalovirus, and herpes simplex virus 1 and 2) and stroke risk in a prospective cohort study.201019901154
analysis of the 3'-variable region of the caga gene from helicobacter pylori strains infecting patients at new york city hospitals.helicobacter pylori infects the gastric mucosa in humans and is a causative agent for peptic ulcer disease (pud) and gastric cancer (gc). caga is produced by h. pylori and is associated with more severe outcomes. caga genes vary at the 3'-region with respect to phosphorylation motifs (epiya-a, -b, -c, or -d) and caga multimerization motifs (cm). this variability may be associated with the clinical outcomes. we examined the variable region of caga genes expressed in h. pylori-infected patients tr ...201323117095
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