Publications

a 45-year experience with surgical treatment of peptic ulcer disease in children.	peptic ulcer disease (pud) requiring surgical treatment has become rare with the availability of modern medical management. a retrospective study of all patients who required operations for pud between 1949 and 1994 (n = 43) was done. the patients were classified into 3 groups: a (n = 38): pre-histamine-2 (h2) blocker era (1949-1975); b (n = 3): pre-hydrogen-potassium (h-k+) atpase inhibitor era (1976-1988); c (n = 2): h-k+ atpase inhibitor era (1989-1994). data, analyzed using x2 analysis (p < ...	1996	8783092
test and treat strategies for helicobacter pylori in uninvestigated dyspepsia: a canadian economic analysis.	recognition of the pivotal role of helicobacter pylori in the pathogenesis of peptic ulcer disease has revolutionized primary care approaches to dyspepsia. decision analysis was used to compare the cost effectiveness of empirical ranitidine with a test and treat strategy using either h pylori serology or the 13carbon-urea breath test (13c-ubt).	2000	10851277
previous exposure to chlamydia pneumoniae, helicobacter pylori and other infections in canadian patients with ischemic heart disease.	previous exposures to chlamydia pneumoniae (cp), helicobacter pylori (hp) or cytomegalovirus (cmv) have been associated with atherosclerotic heart disease. these associations were studied in canadian patients, and the exposure to five infections measured.	2001	11264559
cost effectiveness in canada of a multidrug prepackaged regimen (hp-pac)+ for helicobacter pylori eradication.	to assess the cost effectiveness of a multidrug prepackaged regimen for helicobacter pylori, the hp-pac (lansoprazole 30mg, clarithromycin 500 mg, amoxicillin 1 g, all twice daily), relative to alternative pharmacological strategies in the management of confirmed duodenal ulcer over a 1-year period from 2 perspectives: (i) a strict healthcare payer perspective (ontario ministry of health) excluding the patient copayment; and (ii) a healthcare payer perspective including the patient copayment.	2001	11596835
helicobacter pylori and the prevention of gastric cancer.	helicobacter pylori is an important cause of stomach cancer that infects a substantial proportion of the canadian adult population. h pylori can be detected by noninvasive tests and effectively eradicated by medical treatment. screening for and treatment of h pylori may represent a significant opportunity for preventive oncology.	2004	15152278
iron deficiency and anemia prevalence and associated etiologic risk factors in first nations and inuit communities in northern ontario and nunavut.	anemia is common among children in aboriginal communities in canada. the objectives of this study were to determine the prevalence of anemia and to identify its associated risk factors among young children in aboriginal communities in northern ontario and nunavut.	2005	16625803
dyspepsia in homeless adults.	to determine the prevalence of and risk factors for dyspepsia in a representative sample of homeless persons using shelters in toronto, canada.	2006	16721223
helicobacter pylori infection in ontario: prevalence and risk factors.	helicobacter pylori has been classified by the world health organization as a type i carcinogen. nearly 50% of the world's population is estimated to be infected with h pylori. prevalence patterns of the infection are different between developing and developed countries. the present study had two objectives - to estimate the prevalence of h pylori infection in ontario, and to evaluate the relationship between the infection and various demographic characteristics and selected lifestyle factors.	2007	17703249
low prevalence of helicobacter pylori infection in canadian children: a cross-sectional analysis.	the incidence and prevalence rates of childhood helicobacter pylori infection vary greatly by nation, with infection rates of 8.9% to 72.8% reported in developed and developing countries, respectively. to date, few studies have assessed the prevalence of h pylori in canadian children, with studies limited to aboriginal communities and single tertiary care centres from ontario and quebec.	2008	18478134
neglected infectious diseases in aboriginal communities: haemophilus influenzae serotype a and helicobacter pylori.	this report describes proceedings of a workshop entitled "neglected infectious diseases in aboriginal communities" which took place in thunder bay, ontario, canada, on october 12, 2011. this workshop was jointly organized by the national research council of canada (nrc), the national microbiology laboratory (public health agency of canada) and northern ontario school of medicine (nosm) with participants from the medical sciences division and clinical sciences division of nosm, nrc, national micr ...	2012	23046541
prevalence of helicobacter pylori in a first nations population in northwestern ontario.	to assess prevalence of helicobacter pylori infection, reasons for referral for gastroscopy, and clinical findings of gastroscopy in a symptomatic first nations population in northwestern ontario from 2009 to 2011.	2013	23585621
cost-effectiveness of the carbon-13 urea breath test for the detection of helicobacter pylori: an economic analysis.	this analysis aimed to evaluate the cost-effectiveness of various testing strategies for helicobacter pylori in patients with uninvestigated dyspepsia and to calculate the budgetary impact of these tests for the province of ontario.	2013	24228083