a comparison of microsatellite instability in early onset gastric carcinomas from relatively low and high incidence european populations.we have investigated the genetic basis of gastric carcinomas occurring in patients aged under 40 years from a portuguese population with a relatively high incidence of gastric cancer. we analysed a panel of 12 microsatellite loci in dna extracted from gastric carcinomas arising in 16 patients aged 24-39 years from braga, portugal. overall, microsatellite instability (mi) in at least 1 locus was detected in 44% (7 of 16) of carcinomas. a single patient demonstrated a mutator phenotype suggestive ...200010629076
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