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the effect of 5-year vitamin c supplementation on serum pepsinogen level and helicobacter pylori infection.we conducted a population-based, double-blind, randomized controlled trial to examine the effect of vitamin c supplementation on serum pepsinogen (pg) level, helicobacter pylori (h. pylori ) infection, and cytotoxin-associated gene a (cag a) status. subjects aged 40 to 69 years living in one village in akita prefecture, a high-risk area for gastric cancer in japan, were recruited through annual health check-up programs. among 635 subjects diagnosed as having chronic gastritis on the basis of ser ...200312824908
the administrative project of helicobacter pylori infection screening among junior high school students in an area of japan with a high incidence of gastric cancer.helicobacter pylori infection is a common chronic infection that is closely associated with gastric cancer, known to be decreasing worldwide. we set up an administrative project of screening examination for h. pylori infection in junior high school students in akita prefecture to investigate the current prevalence of h. pylori infection in childhood in an area where the incidence of gastric cancer is particularly high.201728093653
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