Publications

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risk factors for helicobacter pylori infection among a rural population in japan: relation to living environment and medical history.helicobacter pylori infection is related to several gastroduodenal diseases, though the route of transmission remains unclear.200314604222
effect of eradication of helicobacter pylori on incidence of metachronous gastric carcinoma after endoscopic resection of early gastric cancer: an open-label, randomised controlled trial.the relation between helicobacter pylori infection and gastric cancer has been proven in epidemiological studies and animal experiments. our aim was to investigate the prophylactic effect of h pylori eradication on the development of metachronous gastric carcinoma after endoscopic resection for early gastric cancer.200818675689
characteristics and trends of clarithromycin-resistant helicobacter pylori isolates in japan over a decade.clarithromycin has been administered to patients in japan since 1991. clarithromycin-resistant helicobacter pylori strains have been on the rise in japan. we obtained h. pylori isolates between 1989 and 2000 and examined mutations of the 23s rrna gene, which are closely associated with clarithromycin resistance. isolates were obtained from 356 patients with h. pylori infection treated at the hiroshima university. sixty-one of the patients received clarithromycin-based h. pylori eradication thera ...200415051929
reduction in the incidence of helicobacter pylori-associated carcinoma in japanese young adults.helicobacter pylori (hp) is a major risk factor for gastric carcinogenesis. in japan, the incidence of hp infection in young adults has declined markedly. the purpose of this study was to clarify this trend in the incidence of hp-associated gastric carcinoma (gca) in young (under 30 years of age) japanese patients. we enrolled 53 such patients who underwent surgical resection of gca in one of 18 hospitals in the hiroshima prefecture between 1976 and 1999. the patients were classified into groups ...200111295093
prevalence of helicobacter pylori resistance to clarithromycin and metronidazole determined by 23s ribosomal rna and rdxa gene analyses in hiroshima, japan.resistance to antibiotics in helicobacter pylori is increasing and becoming a serious problem in eradication treatment of h. pylori. the prevalence of h. pylori infections that are resistant to clarithromycin, metronidazole, or both were determined in h. pylori isolates in hiroshima, japan.200312974909
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