Publications

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a new cyclo-oxygenase-2 gene variant in the han chinese population is associated with an increased risk of gastric carcinoma.cyclo-oxygenase-2 (cox-2, also known as prostaglandin synthase 2) influences carcinogenesis through regulation of angiogenesis, apoptosis, and cytokine expression. cox-2 is encoded by the gene ptgs2. several studies have suggested that ptgs2 single-nucleotide polymorphisms (snps) are involved in gastrointestinal carcinogenesis. in this study, we observed the ptgs2 val511ala (5939t/c) polymorphism in the chinese population for the first time, and investigated whether this polymorphism might contr ...201021275453
study on the association of cox-2 genetic polymorphisms with risk of gastric cancer in high incidence hexi area of gansu province in china.to investigate the possible association of polymorphisms, cyclooxygenase-2 (cox-2) promoter region -899g>c, cox-2 codon 587g>a, with risk of gastric cancer in the high incidence hexi area of gansu province in china. blood samples from 140 patients with gastric carcinoma and 125 normal persons were collected in hexi area of gansu province in china. polymorphisms of cox-2 -899g>a and cox-2 587g>a were genotyped by pcr-taqman. for detection helicobacter pylori infection, warhin-starry staining was ...201120364406
[epidemiological study on status of helicobacter pylori in children and teenagers in wuwei city, gansu province].to investigate the prevalence of helicobacter pylori (hp) infection among children aged 3 to 18 years old of wuwei city, gansu province.200920137267
campylobacter pylori in patients with gastritis, peptic ulcer, and carcinoma of the stomach in lanzhou, china. 19882896897
gastric atrophy and regional variation in upper gastrointestinal disease.to compare the upper gastrointestinal disease profiles of helicobacter pylori-infected patients drawn from two distinct regions of china, one with a low incidence of gastric cancer (guangzhou) and the other with a high incidence of gastric cancer (lanzhou). the age-standardized prevalence of h. pylori within the populations of these two cities was similar (approximately 56%). in these patient groups, the prevalence of different gastrointestinal disease states and the occurrence and severity of g ...19957611205
incidence and mortality of gastric cancer in china.gastric cancer is one of the most frequent cancers in the world; almost two-thirds of gastric cancer cases and deaths occur in less developed regions. in china, based on two national mortality surveys conducted in 1970s and 1990s, there is an obvious clustering of geographical distribution of gastric cancer in the country, with the high mortality being mostly located in rural areas, especially in gansu, henan, hebei, shanxi and shaanxi provinces in the middle-western part of china. despite a sli ...200616440411
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