| systemic cytokine levels and subsequent risk of gastric cancer in chinese women. | although control of the host cytokine network is known to influence gastric cancer susceptibility, the specific inflammatory responses in gastric carcinogenesis remain unclear. we prospectively examined the relationships between gastric cancer risk and plasma levels of interleukin (il)-1+¦, il-6, il-8 and tumor necrosis factor (tnf)-+¦ in a nested case control study within the shanghai women's health study. two controls were matched to each case on the basis of age, menopausal status, and sample ... | 2011 | 21740481 |
| consensus on chronic gastritis in china--second national consensus meeting on chronic gastritis (14-16 september 2006 shanghai, china). | | 2007 | 17532824 |
| plasma pepsinogens, antibodies against helicobacter pylori, and risk of gastric cancer in the shanghai women's health study cohort. | circulating pepsinogens can indicate atrophic gastritis, a precursor of gastric cancer. we tested the association between gastric cancer and plasma pepsinogens and antibodies against helicobacter pylori in a case-control study nested in a prospective cohort. | 2011 | 21407214 |
| helicobacter pylori infection and gastritis: the systematic investigation of gastrointestinal diseases in china (silc). | helicobacter pylori infection remains common in east asia, though its prevalence is decreasing in western countries. h. pylori-related atrophic gastritis (ag) may reduce the likelihood of gastroesophageal reflux disease (gerd). we investigated the prevalence of h. pylori infection and ag and their association with endoscopic findings and symptom-defined gerd in shanghai. | 2011 | 21198827 |
| comparative genomics profiling of clinical isolates of helicobacter pylori in chinese populations using dna microarray. | in order to search for specific genotypes related to this unique phenotype, we used whole genomic dna microarray to characterize the genomic diversity of helicobacter pylori (h. pylori) strains isolated from clinical patients in china. the open reading frame (orf) fragments on our microarray were generated by pcr using gene-specific primers. genomic dna of h. pylori 26695 and j99 were used as templates. thirty-four h. pylori isolates were obtained from patients in shanghai. results were judged b ... | 2007 | 17342051 |
| regional variation among vaca alleles of helicobacter pylori in china. | allelic variation among helicobacter pylori vaca occurs in the signal and middle region of the gene. the aim of the study was to investigate alleleic variation of vaca among h. pylori strains from three regional areas of china and the relationship between vaca alleles and pud. dna extracted from 88 clinical isolates of h. pylori was analyzed by type-specific pcr and reverse hybridization line probe assay (lipa) to determine the genotype of vaca and presence of caga. in 87 isolates, all of the va ... | 2003 | 12734231 |
| helicobacter pylori "test-and-treat" strategy is not suitable for the management of patients with uninvestigated dyspepsia in shanghai. | the safety of helicobacter pylori "test-and-treat" and "test-and-endoscopy" strategies for the management of young patients with uninvestigated dyspepsia has not been evaluated in shanghai. | 2005 | 16165715 |
| analysis of clinical characteristics of dyspeptic symptoms in shanghai patients. | to improve the management of dyspepsia by analyzing the clinical characteristics of dyspeptic symptoms in patients from shanghai. | 2005 | 15904423 |
| [epidemiological study of helicobacter pylori infection and its risk factors in shanghai]. | to explore the helicobacter pylori (hp) infection status in shanghai and its risk factors. | 2005 | 15949394 |
| helicobacter pylori infection and risk of gastric cancer in shanghai, china: updated results based upon a locally developed and validated assay and further follow-up of the cohort. | infection with helicobacter pylori has been associated with an increased risk of gastric cancer in low-risk populations. however, our previous results (p. m. webb et al., int. j. cancer, 67: 603-607, 1996) from an ongoing prospective study in shanghai, china, a relatively high-risk population, failed to show an association between h. pylori infection and the subsequent risk of gastric cancer. that previous study had a relatively short time period of follow-up and the enzyme-linked immunosorbent ... | 1999 | 10428200 |
| [the genotype of vac a gene of helicobacter pylori (hp) and its correlation with the gastroduodenal diseases associated with hp]. | to analyze the expression of vac a gene of helicobacter pylori (hp) isolated from chinese patients and to find out the relationship between the genotype of hp vac a and the gastroduodenal diseases associated with hp. | 1999 | 11798714 |
| assessment of clarithromycin-resistant helicobacter pylori among patients in shanghai and guangzhou, china, by primer-mismatch pcr. | of 96 helicobacter pylori isolates from patients in shanghai and guangzhou, china, 5 had the a2143g 23s rrna mutation as determined by primer-mismatch pcr and were resistant to clarithromycin by the e-test. the remaining isolates were primer-mismatch pcr negative and susceptible to clarithromycin. the conclusion is that the prevalence of clarithromycin-resistant h. pylori isolates among these chinese patients is 5%. | 2002 | 11773126 |
| an apparent lack of association between helicobacter pylori infection and risk of gastric cancer in china. | several prospective studies have shown a significant association between helicobacter pylori seropositivity and the risk of gastric cancer. only a small proportion of h. pylori-infected individuals will, however, develop gastric cancer, and it is unclear what effects other factors, such as diet, might have on the risk of cancer. eighty-seven subjects with gastric cancer were identified during the first 6 years of follow-up (mean 2.4 years) of a cohort of middle-aged men from shanghai, china. the ... | 1996 | 8782645 |
| seroprevalence of helicobacter pylori infection in medical staff in shanghai. | the epidemiology of helicobacter pylori is still under investigation. it is postulated that the human stomach is the natural reservoir and that spread occurs by oral-oral or fecal-oral transmission. the aim of this study was to determine whether medical staff, especially endoscopy unit personnel, are at an increased risk of acquiring h. pylori infection. | 1996 | 8858741 |
| [prevalence of helicobacter pylori infection among children aged 7 to 18 years old: a school-based cross-sectional study in minhang district of shanghai in 2014]. | to study the infection rate and current infection rate of helicobacter pylori (hp) among children aged 7 to 18 years old in minhang district of shanghai. | 2016 | 27412738 |
| resistance of helicobacter pylori to antibiotics from 2000 to 2009 in shanghai. | to investigate the resistance of helicobacter pylori (h. pylori) to 6 commonly used antibiotics from 2000 to 2009 in shanghai. | 2010 | 20976850 |
| epidemiology of symptom-defined gastroesophageal reflux disease and reflux esophagitis: the systematic investigation of gastrointestinal diseases in china (silc). | gastroesophageal reflux disease (gerd) is thought to be less prevalent in china than in western countries. however, essential population-based endoscopy data are lacking for this country. | 2010 | 20955088 |
| risk factors for peptic ulcer in shanghai. | to investigate the combined effects of helicobacter pylori infection and traditional risk factors for peptic ulcer. | 1996 | 8671567 |
| epidemiology of peptic ulcer disease: endoscopic results of the systematic investigation of gastrointestinal disease in china. | complications of peptic ulcer disease (pud) are common in china. population-based estimates of the prevalence of pud are needed to quantify and characterize the population at risk of these complications. | 2010 | 20736940 |
| alcohol and tobacco use in relation to gastric cancer: a prospective study of men in shanghai, china. | epidemiologic findings of tobacco and alcohol use in relation to gastric cancer are inconsistent. well-designed prospective studies examining their relationship are sparse. | 2010 | 20699372 |
| dyspepsia and irritable bowel syndrome in china: a population-based endoscopy study of prevalence and impact. | dyspepsia and irritable bowel syndrome (ibs) are common in western populations. | 2010 | 20497141 |
| urinary prostaglandin e2 metabolite and gastric cancer risk in the shanghai women's health study. | chronic inflammation has been implicated in the etiology of gastric cancer. prostaglandin e(2) (pge(2)) is one of the major end-products of the cyclooxygenase-2 pathway, an enzyme that is an important mediator of inflammation. using a novel method of quantifying the primary urinary metabolite of pge(2) (pge-m; 11alpha-hydroxy-9,15-dioxo-2,3,4,5-tetranorprostane-1,20-dioic acid), we evaluated urinary pge-m concentrations in association with subsequent risk of development of gastric cancer in the ... | 2009 | 19861525 |
| isothiocyanates, glutathione s-transferase m1 and t1 polymorphisms and gastric cancer risk: a prospective study of men in shanghai, china. | isothiocyanates (itc) in cruciferous vegetables may be chemopreventive against gastric cancer development. glutathione s-transferases (gsts) may modify the chemopreventive effect of itc. the relationship between urinary total itc and risk of gastric cancer was prospectively examined. between 1986 and 1989, 18,244 middle-aged men in shanghai, china were enrolled in a prospective study of diet and cancer and donated baseline urine and blood samples. urinary itc was quantified for 307 incident case ... | 2009 | 19610060 |
| core genome haplotype diversity and vaca allelic heterogeneity of chinese helicobacter pylori strains. | the human gastric pathogen, helicobacter pylori, has co-evolved with its host and established itself in the human stomach possibly millions of years ago. therefore, the diversity of this bacterium is important in its clinical manifestations. our aim has been to evaluate the genetic diversity of 40 h. pylori clinical isolates from four different parts of china. the methods of multi-locus sequence typing and vaca allele genotyping were used to assess their genetic diversity. to discriminate mlst, ... | 2009 | 19452214 |
| abo blood group and risk of pancreatic cancer: a study in shanghai and meta-analysis. | studies over 5 decades have examined abo blood groups and risk of pancreatic cancer in western, asian, and other populations, though no systematic review has been published. we studied data from 908 pancreatic cancer cases and 1,067 population controls collected during december 2006-january 2011 in urban shanghai, china, and reviewed the literature for all studies of this association. random-effects meta-analysis provided summary odds ratio estimates according to blood group and by populations e ... | 2013 | 23652164 |
| clinical relevance of icea and baba2 genotypes of helicobacter pylori in a shanghai population. | to determine the distribution of the icea and baba2 genotypes of helicobacter pylori in patients with various gastroduodenal diseases in shanghai, and to explore the association between genotype and the clinical outcome of infection. | 2004 | 15612889 |
| new dual therapy for primary treatment of helicobacter pylori infection: a prospective randomized study in shanghai, china. | to evaluate the eradication rates, side effects and the patient compliance of a dual therapy with rabeprazole and amoxicillin as the first-line therapy in patients with helicobacter pylori (h. pylori) infection. | 2014 | 25205201 |