Publications

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occurrence, clinical manifestation and the epidemiological implications of naturally occurring canine trypanosomosis in western kenya.domestic dogs were screened for trypanosoma brucei infection using the haematocrit centrifugation technique as part of routine active surveillance exercises in the busia and teso districts of kenya. the purpose was to assess the role of dogs as sentinels for the occurrence of human sleeping sickness. out of 200 dogs screened, five were found to be infected at the various test sites. these five succumbed to the disease within four weeks, and exhibited a distinct and pronounced corneal opacity bef ...200314971734
cattle owners' perceptions of african bovine trypanosomiasis and its control in busia and kwale districts of kenya.a study using a structured questionnaire was conducted in busia district, western kenya and kwale district, coastal kenya to obtain qualitative and quantitative information from 256 cattle owners about their production systems, their perceptions of the diseases encountered in their cattle, the drugs used, and other measures adopted to control trypanosomiasis in cattle. the predominant production system was mixed crop-livestock with farmers owning 2-11 local cattle on holdings between 2 and 5 ha. ...200312711100
isolation of trypanosoma brucei from the monitor lizard (varanus niloticus) in an endemic focus of rhodesian sleeping sickness in kenya.monitor lizards were sampled along the shores of lake victoria to detect natural infections of potentially human-infective trypanosomes. in an area with endemic rhodesian sleeping sickness, one of 19 lizards was infected (busia, kenya). six of ten lizards also showed indirect evidence of infection with trypanosoma brucei (antibody elisa). in an area with no recent history of human disease (rusinga island), no parasites were found and no antibodies to t. brucei were detected. the isolate was iden ...199910206114
trypanosoma brucei: comparison of circulating strains in an endemic and an epidemic area of a sleeping sickness focus.human sleeping sickness in east africa is characterized by periods of long-term endemicity interspersed with short-term epidemics. the factors generating these huge changes are largely uncharacterized but probably reflect complex interactions among socioeconomic factors, ecological factors, and the movement and diversity of trypanosome strains. to investigate the role of trypanosome strains in the generation of these epidemics, we addressed two important questions. (1) are the trypanosome strain ...19989603485
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