an assessment of the effectiveness of the measles immunization programme in lagos, nigeria. 19817271359
potency status and efficacy of measles vaccine administered in nigeria: a case study of three epi centres in lagos, nigeria.the potency status and efficacy of measles vaccines were studied in three immunization (epi) centres in the suburban area of lagos, nigeria. a total of 14 vials of measles vaccine were collected and subjected to potency testing while, 203 measles-vaccinated children were recruited for this study. only 85 (41.87%) of the vaccinees reported back for the post-vaccination follow-up screening. the seroconversion pattern showed that 51(60%) had potent antibody titres ranging from 1:40 to 1:1280, while ...199911205835
molecular epidemiology of nigerian and ghanaian measles virus isolates reveals a genotype circulating widely in western and central africa.sub-saharan africa is one of the regions of the globe with the highest measles-related morbidity and mortality. yet only seven virus isolates from this vast region have been phylogenetically characterized on the basis of their nucleoprotein, the last one in 1991. to characterize the prevalent wild-type viruses and to understand their circulation pattern, a large panel (n = 45) of isolates was collected in ghana and nigeria in 1997 and 1998. on the basis of their nucleoprotein sequence, the virus ...199910211955
optimal age for vaccinating nigerian children against measles. ii. seroconversion to measles vaccine in different age groups.ninety-eight children between five and nine months were given measles vaccine. bloodsamples were taken before and again six to eight weeks after immunization and tested for haemagglutination inhibition antibodies to measles virus. it was found that the sero-conversion rate was significantly lower (p less than 0.05) in infants under seven months than over this age. the results suggest that although some immunized at six months of age show seroconversion, the proportion is too small to justify ext ...19817342385
measles hi-antibody levels in lagos children, nigeria: a follow-up study to resurgence of measles in lagos metropolis.a total of 138 children aged between 0-36 months were bled and screened for measles haemagglutination inhibiting (hi)-antibody. twenty seven children were from age group (0-4) months with 16 (59.3%) seropositive while, 67 and 44 were bled in the group (5-9) and > or = 12 months with 29 (43.3%) and 31 (70.5%) sero positive sera respectively. the distribution of the antibody titre pattern among various age groups suggest vaccination against measles should be at age 9 month. the antibody titres pat ...200111922159
optimal age for vaccinating nigerian children against measles. i. neonatal antibody profile and subsequent susceptibility to measles.the decline of maternally acquired haemagglutination inhibiting antibodies against measles virus in nigerian children born in lagos was studied. at birth all the 303 children whose cord blood serum was tested had measurable antibodies. the antibody titre remained detectable in all the children up to four months of age, and in over 90% at five months of age. at six months 65% of the children were without detectable antibodies. at seven and eight months the proportion of children without measurabl ...19817342384
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