[epidemiological study on respiratory syncytial virus lower respiratory tract infections in northern hokkaido, japan].we carried out an epidemiological study on lower respiratory tract infections, concerning the respiratory syncytial virus (rsv) infection, in northern hokkaido, japan, during the 2-year-study period from april 1991 to march 1993. there were 467 hospitalized patients with lower respiratory tract infections. we examined the presence of rsv antigen in their nasopharyngeal specimens of 456 out of 467 patients (97.6%) by enzyme immunoassay. the diagnosis of mycoplasma pneumoniae infection was done by ...19948138666
epidemiological and molecular studies of measles at different clusters in hokkaido district, japan, 2007 eight epidemic clusters (more than 15 cases in each) and other sporadic cases of measles occurred in hokkaido district, japan. a total of 850 cases were identified. approximately half of them were > or = 15 years of age, resulting in a huge public health problem in the community associated with school closings, and 31% of the cases reported that they already had a history of vaccination. of 28 isolates of the measles virus detected, all were identified as genotype d5, identical to the ty ...200919468183
Progress toward measles elimination between 2008 and 2010 in the Hokkaido district, Japan. 201121937832
detection of measles virus genotypes b3, d4, d5, d8, and h1 in the surveillance system in hokkaido, japan, 2006-2015, the last decade toward the elimination.measles is an acute and highly contagious disease caused by measles virus (mev). the government of japan, following the last epidemic in 2007 and 2008, which was caused by genotype d5 strains, introduced a catch-up-vaccination program for teenagers during japan fiscal years 2008-2012 and a mandatory case-based reporting system for the nationwide elimination. furthermore, laboratory confirmation of measles cases by genotyping of isolates has been performed to clarify the source of infection and s ...201728003595
recent progress toward measles elimination in hokkaido, japan, during 2011-2012.laboratory diagnoses for measles were performed in a total of 97 cases in hokkaido, japan, during 2011-2012. two patients were confirmed to be positive for measles virus (mv), both of whom lived in the iburi district of hokkaido. molecular analysis of the nucleotide sequences of the nucleoprotein (n) gene revealed that these 2 strains had high homology with each other and belonged to the genotype d8. the onset interval of these cases and epidemiological data suggested that mv transmission had oc ...201425056081
my continuing efforts toward the eradication of the vaccine-preventable diseases from japan.when compared to the western countries, unfortunately, the progress toward the eradication of vaccine-preventable diseases in japan has been relatively slow and hampered by some problems inherent to japan. concerning this, i have been working on the vaccine-preventable diseases, that is, measles, influenza, haemophilus influenzae, and streptcoccus pneumoniae infections. my first work was to produce monoclonal antibodies against measles virus proteins, and by using these antibodies, i established ...201121802468
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