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variation in field isolates of measles virus during an 8-year period in japan.field isolates of measles virus (mv) during an 8-year period in four areas of japan, i.e., osaka, nagoya, tokyo and akita, were classified into three types in regard to the electrophoretic mobility of the hemagglutinin (ha) proteins: s type with small (78k) ha, m type with intermediate (80 k) ha and l type with large (82 k) ha. the type of field isolates was closely related with the geographical location and the year of virus isolation. the s type strain was isolated only in an outbreak from 198 ...19938321151
isolation of a wild type measles virus classified as genotype h1 in osaka city. 200212501261
an outbreak of measles classified as genotype h1 in 2008 in osaka prefecture. 200919168968
co-circulation of two genotypes of measles virus and mutual change of the prevailing genotypes every few years in osaka, japan.genotypes of 44 wild-type measles virus (mv) strains isolated in osaka, japan, during 1997-2001, were determined based on phylogenetic analyses of a 456-nt 3' terminal nucleoprotein gene sequence with the reference mv strains designated by the world health organization. the wild-type mv strains were classified into two genotypes, d3 and d5, recognized as indigenous in japan. six of 12 strains isolated in 1997 were classified into genotype d3 and the other 6 into d5. eleven of 13 strains were d3, ...200312683418
alterations and diversity in the cytoplasmic tail of the fusion protein of subacute sclerosing panencephalitis virus strains isolated in osaka, japan.we determined the nucleotide sequence of the fusion (f) gene of three strains (osaka-1, -2, and -3) of nonproductive variants of measles virus (mv). these viral strains were isolated in osaka, japan, from brain tissues of patients with subacute sclerosing panencephalitis (sspe). phylogenetic analysis revealed a close relationship among the three strains of sspe virus. the cytoplasmic tail of the f protein, predicted from sequence analysis of the gene, is altered in all three sspe strains when co ...200212076836
hemadsorption expressed by cloned h genes from subacute sclerosing panencephalitis (sspe) viruses and their possible progenitor measles viruses isolated in osaka, japan.most subacute sclerosing panencephalitis (sspe) viruses, including our osaka-1, -2, and -3 strains isolated in osaka, have shown negative hemadsorption (had) by african green monkey red blood cells. this property has been thought to be characteristic of sspe virus as compared to the positive reaction of the standard edmonston strain of measles virus (mv). however, this assumption has become quite obscure because mv mutates frequently at the genetic level during its multiplication and also becaus ...200111270608
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