Publications

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annual colposcopies and pap smears recommended for women with hiv.a new study presented by annekathryn goodman of massachusetts general hospital indicates that hiv positive women should receive annual colposcopies, along with pap smears, to detect abnormal cell growth early. the recommendation is due to the fact that hiv positive women are more likely to have false-negative pap smears than hiv negative women. in a related development, the fda approved a new dna-based blood test to detect human papillomavirus, which is associated with cervical and anal cancer. ...199911366700
global dna methylation level in whole blood as a biomarker in head and neck squamous cell carcinoma.head and neck squamous cell carcinoma (hnscc) is commonly associated with tobacco and alcohol exposures, although dietary factors, particularly folate, and human papillomavirus, are also risk factors. epigenetic alterations are increasingly implicated in the initiation and progression of cancer. genome-wide (global) hypomethylation seems to occur in early neoplasia and is a feature of genomic dna derived from solid tumor tissues, including hnscc. this study aimed to determine whether global meth ...200717220338
using the rate of positive high-risk hpv test results for asc-us together with the asc-us/sil ratio in evaluating the performance of cytopathologists.we reviewed our experience with 2 indicators of cytopathologist performance: the relative frequency of the interpretations atypical squamous cells of undetermined significance (asc-us) and squamous intraepithelial lesion (sil) and the frequency of positive test results for high-risk human papillomavirus (hr-hpv) dna associated with a cytologic interpretation of asc-us. data derived for 9 cytopathologists were reviewed. asc-us/sil ranged from 0.99 to 4.02 (mean, 1.77) in 2005 and from 0.82 to 3.6 ...200818089494
multicenter study of knowledge about human papilloma virus and attitudes among emergency department patients.we sought to evaluate knowledge of human papilloma virus (hpv) and attitudes toward the hpv vaccine among emergency department (ed) patients.200919576825
college men's knowledge, attitudes, and beliefs about the human papillomavirus infection and vaccine.men enrolled in an urban university participated in focus groups (k=6; n=45) to explore knowledge about human papillomavirus and attitudes toward prophylactic vaccine. results suggest that regardless of whether vaccines become available to men, educational efforts should include them, as men tend to have many misconceptions and do not perceive themselves to be vulnerable.200919837363
sexually transmitted disease (std) diagnoses and mental health disparities among women who have sex with women screened at an urban community health center, boston, ma, 2007.a growing body of research documents mental health disparities among women who have sex with women (wsw) compared with women who have sex with men only (wsm). however, there remains a dearth of research exploring these indicators alongside sexually transmitted diseases (stds) and wsw sexual health.201020118673
national, state, and local area vaccination coverage among adolescents aged 13-17 years --- united states, 2009.the advisory committee for immunization practices (acip) recommends that adolescents routinely receive the following vaccines: meningococcal conjugate (menacwy, 1 dose); tetanus, diphtheria, acellular pertussis (tdap, 1 dose); and (for females) human papillomavirus (hpv, 3 doses). adolescents also should receive the following recommended vaccinations they missed during childhood: measles, mumps, rubella (mmr, 2 doses); hepatitis b (hepb, 3 doses); and varicella (var, 2 doses). since 2006, cdc ha ...201020724968
parents' opinions of mandatory human papillomavirus vaccination: does ethnicity matter?to explore parents' opinions of school-entry requirements for human papillomavirus (hpv) vaccination.201021051001
minimally abnormal pap testing and cervical histology in hiv-infected women.abstract objective: to assess the underlying histology of hiv-infected women with minimally abnormal pap tests compared to hiv-uninfected women by evaluating their colposcopic and histologic outcomes. methods: retrospective analysis was performed to identify hiv-infected women who had at least one cervical pap test from 2002 through 2008 at boston medical center. we identified women who underwent colposcopy within 6 months of a minimally abnormal pap test (atypical squamous cells of undeterm ...201122011239
Confusion regarding cervical cancer screening and chlamydia screening among sexually active young women.ObjectiveThe American Congress of Obstetricians and Gynecologists (ACOG) recently recommended that cervical cancer screening begin at 21 years of age and occur biennially for low-risk women younger than 30 years. Earlier studies suggested that women may have limited understanding of the differences between cervical cancer screening and chlamydia screening. This study assessed the knowledge of chlamydia and cervical cancer screening tests and schedules in younger women.MethodsA survey regarding k ...201122123163
national and state vaccination coverage among adolescents aged 13 through 17 years--united states, 2010.the advisory committee on immunization practices (acip) recommends that adolescents routinely receive meningococcal conjugate (menacwy, 2 doses); tetanus, diphtheria, acellular pertussis (tdap, 1 dose); and human papillomavirus (hpv, 3 doses) vaccines (influenza vaccine is recommended annually for all persons aged 6 months and older). cdc tracks vaccination coverage among adolescents aged 13 through 17 years through the national immunization survey--teen (nis-teen). to provide updated vaccinatio ...201121866084
model-based analyses to compare health and economic outcomes of cancer control: inclusion of disparities.disease simulation models of the health and economic consequences of different prevention and treatment strategies can guide policy decisions about cancer control. however, models that also consider health disparities can identify strategies that improve both population health and its equitable distribution.201121900120
prevalence of abnormalities influences cytologists' error rates in screening for cervical cancer.medical screening tasks are often difficult, visual searches with low target prevalence (low rates of disease). under laboratory conditions, when targets are rare, nonexpert searchers show decreases in false-positive results and increases in false-negative results compared with results when targets are common. this prevalence effect is not due to vigilance failures or target unfamiliarity.201122129183
anal human papillomavirus infection is associated with hiv acquisition in men who have sex with men.human papillomavirus (hpv) is a common sexually transmitted agent that causes anogenital cancer and precancer lesions that have an inflammatory infiltrate, may be friable and bleed. our aim was to determine the association between anal hpv infection and hiv acquisition.200919390418
effect of patient age on outcomes and compliance in women with minimally abnormal pap tests.to assess follow-up and histologic outcomes by age for an indigent urban cohort of women with minimally abnormal cytology.201020795351
giving it our best shot? human papillomavirus and hepatitis b virus immunization among refugees, massachusetts, 2011-2013.the receipt rate of hepatitis b virus vaccine among adolescents in the united states is high, while the receipt rate of human papillomavirus vaccine is low. rates have not been closely studied among refugees, whose home countries have high rates of disease caused by these viruses.201728641071
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