Publications

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duration and clearance of anal human papillomavirus (hpv) infection among women: the hawaii hpv cohort study.the association of anal cancer with human papillomavirus (hpv) infection is well established; however, little is known about the epidemiology of anal hpv in healthy women. we investigated patterns of duration and clearance of anal hpv infection in a cohort of healthy women in hawaii.200919191636
informational needs and the experiences of women with abnormal papanicolaou smears.to describe the experience of women with abnormal papanicolaou (pap) smears with a particular focus on their informational needs.200818786022
sequential acquisition of human papillomavirus (hpv) infection of the anus and cervix: the hawaii hpv cohort study.relatively little is known about the epidemiology of anal human papillomavirus (hpv) infection in healthy women and its association with cervical hpv infection.201020307204
plasma micronutrients and the acquisition and clearance of anal human papillomavirus infection: the hawaii hpv cohort study.anal human papillomavirus (hpv) infection is common among women and the cause of most anal malignancies. the incidence of anal cancer has been increasing among u.s. women, yet few cofactors for the natural history of anal hpv infection have been identified. we examined the hypothesis that plasma carotenoid, retinol, and tocopherol concentrations are associated with the acquisition and clearance of anal hpv infection in a cohort of 279 hawaiian residents followed at 4-month intervals for a mean d ...201020935226
the influence of multiple human papillomavirus types on the risk of genotype-concordant incident infections of the anus and cervix: the hawaii hpv cohort study.the influence of multiple human papillomavirus (hpv) types on detection of concordant incident hpv infections of the cervix or anus following infection at the other anatomic site was examined in a cohort of 897 women. multiple hpv infections at the anus were not significantly associated with subsequent acquisition of a concordant cervical infection, whereas prior coinfections in the cervix increased risk of a new cervical hpv infection. incident anal hpv infections following concordant cervical ...201021208924
a tailored multi-media campaign to promote the human papillomavirus cohort study to young women.human papillomavirus (hpv), a sexually transmitted disease, is now recognized as the major cause of cervical cancer. the cancer research center of hawaii developed a low-cost and culturally sensitive multimedia campaign to recruit oahu women to their hpv cohort study, specifically targeting women 18 to 35 years of age.200415916999
circumcision and human papillomavirus infection in men: a site-specific comparison.lack of circumcision has been identified as a risk factor for male genital human papillomavirus (hpv) infection, although this association has not been consistently supported.200818284369
anal human papillomavirus infection in women and its relationship with cervical infection.human papillomavirus (hpv), the primary cause of cervical cancer, is also associated with the development of anal cancer. relatively little is known about the epidemiology of anal hpv infection among healthy females and its relationship to cervical infection. we sought to characterize anal hpv infection in a cohort of adult women in hawaii. overall, 27% (372 of 1,378) of women were positive for anal hpv dna at baseline compared with 29% (692 of 2,372) with cervical hpv dna. among women with pair ...200516284377
the association of plasma micronutrients with the risk of cervical dysplasia in hawaii.limited data from hematological studies suggest that certain nutrients, including carotenoids, tocopherols, and vitamin c, may protect against malignant change in cervical tissue. recognizing that human papillomavirus (hpv) infection induces most neoplastic transformation of cervical tissue, the authors conducted a case-control study to examine the association of plasma micronutrient concentrations with the risk of cervical dysplasia after careful adjustment for hpv infection, using a sensitive ...19989641499
understanding cervical cancer prevention and screening in chuukese women in hawaii.cervical cancer is the primary cause of death due to cancer in women in chuuk state, federated states of micronesia. the chuukese population is the fastest growing segment of the micronesian community in hawaii. little is known about the health beliefs or practices of this population in hawaii. the purpose of this project was to describe the knowledge, attitudes, and beliefs of chuukese women in hawaii regarding cervical cancer prevention and screening.201020539995
acquisition of anal human papillomavirus (hpv) infection in women: the hawaii hpv cohort study.the majority of anal cancer is associated with human papillomavirus (hpv) infection, yet little is known about women's risk of acquisition of anal hpv infection.200818429348
reports: plasma and dietary phytoestrogens and risk of premalignant lesions of the cervix.a number of epidemiological studies have observed an inverse association between phytoestrogens and risk of certain hormonally dependent cancers. we undertook an exploratory analysis of the relationship between specific phytoestrogens and premalignant cervical lesions. a case-control study of 122 women with histologically confirmed cervical squamous intraepithelial lesions (sils) of the cervix and 183 cytologically normal controls was conducted from 1992 to 1996 in honolulu, hawaii. a cervical c ...200415489203
prevalence, acquisition, and clearance of cervical human papillomavirus infection among women with normal cytology: hawaii human papillomavirus cohort study.few natural history studies of cervical human papillomavirus (hpv) incidence and duration have been conducted among older women, especially from multiethnic populations. viral and nonviral determinants of hpv acquisition and clearance were examined among 972 sexually active women, ages 18 to 85 years, recruited from clinics on oahu, hawaii, and followed for a mean duration of 15 months (range, 2-56 months). interviews and cervical cell specimens for cytology and hpv dna detection by pcr, using t ...200818974124
hawaii cohort study of serum micronutrient concentrations and clearance of incident oncogenic human papillomavirus infection of the cervix.the degree to which the resolution of human papillomavirus (hpv) infection parallels exposure to other factors, particularly those related to nutritional status, is a relatively unexplored area of research. we established a cohort of women for long-term follow-up to examine the association of serum retinol, carotenoid, and tocopherol concentrations with the clearance of incident cervical hpv infection. interviews and biological specimens were obtained at baseline and at 4-month intervals. at eac ...200717553901
cervical cytokines and clearance of incident human papillomavirus infection: hawaii hpv cohort study.mechanisms for the control and resolution of human papillomavirus (hpv) infection of the cervix include the local production of cytokines, which control recruitment and function of cells integral to pathogen control. we established a cohort of women for long-term follow-up to examine the mucosal expression of antiviral (ifn-α2), type-1 (ifn-γ, il-12), regulatory (il-10), and proinflammatory (il-1α, il-1β, il-6, il-8, mip-1α, and tnf) cytokines in association with the clearance of incident cervic ...201323436563
promoting and providing hpv vaccination in hawaii: barriers faced by health providers.despite the availability of hpv prophylactic vaccines, uptake has been suboptimal in the us. in the state of hawaii, hpv vaccine coverage has decreased among females and remains low among males aged 13-17. the reasons for low uptake are unknown and may indicate the existence of critical barriers to hpv vaccination. the purpose of this investigation was to identify policy, system and environmental barriers and promoters of pediatric hpv vaccination in hawaii. an online 86-item survey addressing k ...201627038960
human papillomavirus-associated carcinomas in hawaii and the mainland u.s.to the authors' knowledge, human papillomavirus (hpv)-associated carcinomas in hawaii have not been studied in detail.200010717631
local studies address a previously hidden sexually transmitted disease: human papillomavirus and cervical neoplasia. 200111802562
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