Publications

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vaginal microbial flora as a cofactor in the pathogenesis of uterine cervical intraepithelial neoplasia.the vaginal microbial flora of 106 women with histopathologically confirmed cervical intraepithelial neoplasia and 79 women without disease, was evaluated for gardnerella vaginalis, trichomonas vaginalis, candida albicans and other yeasts. flora morphology was assessed by gram staining of secretions. cervical cultures were examined for herpes simplex virus, cytomegalovirus and neisseria gonorrhoeae. chlamydia trachomatis antigens in cervical secretions were detected by enzyme immunoassay. human ...19921351005
factors associated with human papillomavirus infection detected by polymerase chain reaction among urban canadian aboriginal and non-aboriginal women.to determine the prevalence and correlates of human papillomavirus (hpv) infection among women attending an ethnically mixed, predominantly low-income, inner-city primary care clinic.19979153740
costs of colposcopy services and their impact on the incidence and mortality rate of cervical cancer in canada.organized cervical cancer screening services consisting of conventional papanicolaou cervical smears, colposcopy, and related treatment modalities are readily available in all provinces. the purpose of this report was to study the impact of colposcopy usage and costs on cervical cancer incidence and mortality rates in several canadian provinces. knowledge of such information is essential before newer technology such as liquid-based cytology and human papillomavirus testing is introduced or repla ...200516044056
twenty-year trends in the incidence and prevalence of diagnosed anogenital warts in canada.a vaccine has recently been licensed in many countries that protects against the human papillomavirus types 6, 11, 16, and 18. types 6 and 11 account for approximately 90% of anogenital warts (agws). we describe the 20-year trends in the incidence and prevalence of agws in manitoba, canada.200919556932
the manitoba human papillomavirus vaccine surveillance and evaluation system.with the recent introduction of a human papillomavirus (hpv) vaccine in canada, it is important to establish surveillance and evaluation programs that not only track the uptake of the vaccine, but also assess its safety and its impact on: distribution of hpv type, cervical cancer screening programs, the incidence of anogenital warts, precancerous lesions and various cancers, and sexual behaviour.201020632523
can high overall human papillomavirus vaccination coverage hide sociodemographic inequalities? an ecological analysis in canada.human papillomavirus (hpv) vaccination programs have been implemented in more than 50 countries. these programs offer tremendous promise of reducing hpv-related disease burden. however, failure to achieve high coverage among high-risk groups may mitigate program success and increase inequalities. we examined sociodemographic inequalities in hpv vaccination coverage in 4 canadian provinces (quebec (qc), ontario (on), manitoba (mb), british columbia (bc)).201626954465
increasing incidence of anogenital warts with an urban-rural divide among males in manitoba, canada, 1990-2011.anogenital warts (agw) are caused by the most common sexually transmitted infection, human papillomavirus. the objective of this study was to examine agw incidence from 1990 to 2011 by sex, age, income quintile, and residential area category (urban/rural). the study period included the initiation of school-based hpv vaccination for girls in the sixth grade, which began in 2008. the data presented in this paper may also be useful for establishing baseline rates of agw incidence which may be used ...201626939696
effectiveness of the quadrivalent human papillomavirus vaccine against cervical dysplasia in manitoba, canada.effectiveness of the quadrivalent human papillomavirus (qhpv) vaccine against cervical dysplasia has not been estimated using population-based individual level data. we assessed the vaccine effectiveness (ve) of the qhpv vaccine against cervical dysplasia using data collected routinely in manitoba.201424395857
human papillomavirus vaccination and pap testing profile in manitoba, canada.females who receive the human papillomavirus (hpv) vaccine may believe they are protected from developing cervical cancer and no longer require screening. concern has also been expressed that vaccinated females are those that would be screened regularly. this study assesses the pap testing behavior of vaccinated and non-vaccinated females.201324211170
quantifying the impact of dissimilar hpv vaccination uptake among manitoban school girls by ethnicity using a transmission dynamic model.gardasil, a human papillomavirus (hpv) vaccine, began among grade 6 girls in manitoba, canada in 2008. in manitoba, there is evidence that first nations, métis, and inuit women (fnmi) have higher hpv prevalence, lower invasive cervical cancer (icc) screening, and higher icc incidence than all other manitoban (aom) women. we developed a mathematical model to assess the plausible impact of unequal vaccination coverage among school girls on future cervical cancer incidence.201323933332
comparative models of cervical cancer screening in manitoba.the laboratory system in manitoba for routine cervical screening is outdated and costly. we developed a costing framework for the implementation of new cervical cancer screening technology models. the direct healthcare costs in the baseline model, the conventional papanicolaou smear test, were compared with estimates of two newer technology platforms, liquid-based cytology and human papillomavirus (hpv) testing. the findings revealed that hpv testing as a primary screening model for women aged 3 ...201324863312
distribution of human papillomavirus types, cervical cancer screening history, and risk factors for infection in manitoba.we conducted a study to investigate the prevalence of human papillomavirus (hpv) infections in an opportunistic sample of women in manitoba, canada. we inquired about risk factors associated with hpv infections and linked the hpv typing results with the cervical cancer screening history of the participants.201223046799
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