| high-risk human papillomavirus infection and overexpression of p53 protein in squamous cell carcinoma of the esophagus from japan. | the present study was undertaken in order to investigate the possible involvement of high-risk human papillomavirus (hpv; types 16 and 18) or the overexpression of p53 protein in 123 japanese patients with esophageal squamous cell carcinoma (scc) from five different institutions. we detected hpv dna in 30.1% (37/123) by in situ hybridization (ish). of these 123 cases, hpv type 16 was detected in 22 cases and hpv type 18 in 23 cases. in addition, hpv types 16 and 18 were detected simultaneously i ... | 1998 | 9844797 |