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bordetella pertussis serotypes in the united states.to determine the bordetella pertussis serotypes currently causing whooping cough in the united states, recently isolated cultures from different geographic areas were studied. specific adsorbed antisera were prepared in our laboratory and used in both tube and slide agglutination tests. among the 177 cultures isolated during 1966 and 1967 in seven states and one canadian province, the predominant serotype was 1.3 (or 1.3.6), represented by 85% of the cultures. fifteen cultures were serotype 1.2. ...19694312923
evidence for transmission of pertussis in schools, massachusetts, 1996: epidemiologic data supported by pulsed-field gel electrophoresis studies.in 1996, 18 of 20 pertussis outbreaks reported in massachusetts occurred in schools. pertussis surveillance data were reviewed and a retrospective cohort study was conducted in a high school that experienced an outbreak. bordetella pertussis isolates from 9 school cases and from 58 cases statewide were examined by use of pulsed-field gel electrophoresis (pfge). statewide incidence rates were highest among children aged <1 year, 10-14 years, and 15-19 years (106, 117, and 104 cases per 100,000, r ...200010608769
the increasing incidence of pertussis in massachusetts adolescents and adults, 1989-1998.from 1989 to 1998, the incidence of pertussis increased in massachusetts adolescents and adults, reaching 71 and 5 per 100,000, respectively, by 1998, whereas the incidence in children remained stable. by 1998, 92% of cases occurred in adolescents and adults. nationally, in contrast, adolescents and adults had incidences of only 5 and 0.8 per 100,000, respectively, and accounted for 47% of cases. the availability of a specific serologic test and active surveillance by public health personnel in ...200011023464
surveillance for transmission and antibiotic adverse events among neonates and adults exposed to a healthcare worker with pertussis.during a hospital obstetric rotation, a medical student demonstrated classic symptoms of pertussis. the diagnosis was confirmed by isolation of bordetella pertussis. because this exposure occurred in a high-risk hospital setting, control measures were undertaken to prevent transmission and illness.200415566032
impact of bordetella pertussis exposures on a massachusetts tertiary care medical system.to assess the impact of outbreaks of bordetella pertussis infection on a tertiary care medical system.200717520545
outbreaks of respiratory illness mistakenly attributed to pertussis--new hampshire, massachusetts, and tennessee, 2004-2006.pertussis, or whooping cough, is a highly infectious, nationally notifiable respiratory disease associated with prolonged cough illness and paroxysms of coughing, inspiratory "whoop," or posttussive vomiting. reported pertussis cases have tripled in the united states since 2001, with 25,616 probable or confirmed cases reported in 2005. this increase has been attributed to increased circulation of bordetella pertussis, waning vaccine-induced immunity among adults and adolescents, heightened aware ...200717717512
response to an education program for parents about adult pertussis vaccination.we designed a prospective study to evaluate the effectiveness of an educational intervention designed to increase awareness and knowledge of pertussis among parents and grandparents of newborns. we also evaluated its effect on their willingness to receive the tetanus toxoid-diphtheria toxoid-acellular pertussis vaccine. there was a statistically significant (p < .05) increase in participants' knowledge about pertussis and in their willingness to receive vaccination after our education program. h ...200919419326
imperfect vaccine-induced immunity and whooping cough transmission to infants.whooping cough, caused by b. pertussis and b. parapertussis, has increased in incidence throughout much of the developed world since the 1980s despite high vaccine coverage, causing an increased risk of infection in infants who have substantial disease-induced mortality. duration of immunity and epidemically significant routes of transmission across age groups remain unclear and deserve further investigation to inform vaccination strategies to better control pertussis burden. the authors analyze ...201021034823
natural immune boosting in pertussis dynamics and the potential for long-term vaccine failure.incidence of whooping cough, unlike many other childhood diseases for which there is an efficacious vaccine, has been increasing over the past twenty years despite high levels of vaccine coverage. its reemergence has been particularly noticeable among teenagers and adults. many hypotheses have been put forward to explain these two patterns, but parsimonious reconciliation of clinical data on the limited duration of immunity with both pre- and postvaccine era age-specific incidence remains a chal ...201121422281
boosting understanding of pertussis outbreaks. 201121508325
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