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under-recognized pertussis in adults from asian countries: a cross-sectional seroprevalence study in malaysia, taiwan and thailand.surveillance data on the burden of pertussis in asian adults are limited. this cross-sectional study evaluated the prevalence of serologically confirmed pertussis in adults with prolonged cough in malaysia, taiwan and thailand. adults (⩾19 years) with cough lasting for ⩾14 days without other known underlying cause were enrolled from outpatient clinics of seven public and/or private hospitals. single blood samples for anti-pertussis toxin antibodies (anti-pt igg) were analysed and economic impact ...201526468043
antigenic divergence of bordetella pertussis isolates in taiwan.in recent studies, antigenic divergence has been observed in bordetella pertussis circulating isolates. we collected 80 bordetella pertussis isolates in taiwan from 1998 to 2004 and analyzed them using a combination of pulsed-field gel electrophoresis (pfge) and sequencing of the ptxs1 and prn genes. the incidence of pertussis increases every 3 years, and most of the isolates prevalent since 1998 have expressed nonvaccine ptxs1a and prn2 alleles. through pfge analysis, all isolates could be clas ...200516272470
molecular epidemiology of bordetella pertussis in taiwan, 1993-2004: suggests one possible explanation for the outbreak of pertussis in 1997.pertussis reemerges periodically despite high pertussis vaccination coverage in many countries. we used prn and fim3 gene sequences and pulsed-field gel electrophoresis (pfge) to analyze the molecular epidemiology of 168 clinical isolates of bordetella pertussis during 1993-2004, and deduced possible reasons for an outbreak in 1997 in taiwan. in taiwan, during 1996-1997, a shift of prn1 to prn2 was reflected in a transition of pfge group i to group iiia; during 2000-2001, the change from fim3a t ...200616828571
antimicrobial susceptibility testing of bordetella pertussis in taiwan prompted by a case of pertussis in a paediatric patient.in taiwan, pertussis is a notifiable disease with a low incidence in recent years, and antimicrobial susceptibility testing for the causative agent, bordetella pertussis, has not been reported to date. in may 2007, the centers for disease control, taiwan, was informed of a 1-month-old pertussis patient who did not respond to erythromycin treatment. in this study, we report the result of antimicrobial susceptibility testing performed for the suspected erythromycin-resistant isolate, as well as fo ...200819018032
immunogenicity and reactogenicity of a reduced-antigen-content diphtheria-tetanus-acellular pertussis vaccine in healthy taiwanese children and adolescents.disease caused by bordetella pertussis is increasingly being identified among older children and adults in immunized populations, indicating a waning of the vaccine-induced immunity. these findings suggest the need for booster immunization of older children and adults. modern acellular reduced-antigen-content vaccines have been developed, which can be given as a booster in individuals more than 4 years of age. this study was to assess the immunogenicity and reactogenicity of boostrix, glaxosmith ...200516310132
a national seroepidemiologic survey of pertussis among school children in taiwan.in 2009, a booster dose of acellular pertussis vaccine for children at or before entry to elementary school was added to the national immunization program in taiwan, which includes pertussis vaccination at 2, 4, 6, and 18 months of age. in 2013, a study to assess the level of humoral immunity against pertussis in elementary and junior high school children and adolescents was conducted.201728737625
survey of pertussis in patients with prolonged cough.pertussis is an acute respiratory tract illness resulting from bordetella pertussis. widespread use of pertussis vaccine over the past 50 years has decreased the incidence of pertussis. the incidence of pertussis in adolescents and adults has increased in many areas of the world. this study aimed to evaluate the etiologic role of b. pertussis in patients with prolonged cough in taiwan.200616440124
pertussis seroepidemiology in taipei.we evaluated the seroprevalence of pertussis among apparently healthy taipei residents.200010820955
molecular epidemiology of bordetella pertussis isolated in taiwan, 1992-1997.in taiwan, the number of pertussis cases including various types of infection has been increasing in recent years, especially in 1997. since 71% of the reported cases concentrated in the densely populated taipei metropolitan area, concerns have been raised that a highly contagious strain of bordetella pertussis might have appeared in taipei. in this study, 114 strains of b. pertussis including those isolated in 1992-1996 (n = 53) and 1997 (n = 61) were subjected to pulsed-field gel electrophores ...200314695439
bordetella pertussis infection in northern taiwan, 1997-2001.the clinical presentations of laboratory-confirmed bordetella pertussis infection in chang gung children's hospital during 1997 and 2001 were analyzed. of the 46 cases, 25 (54.3%) were male. the patients ages ranged from 24 days to 37 years, with a mean and median of 4.3 years and 10.5 years, respectively. forty four patients had vaccination records, among them 23 patients (52.2%) had received > or = 3 doses of pertussis vaccine. of the patients who were partially vaccinated (received 1 or 2 dos ...200415497010
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