a novel ctx-m beta-lactamase (ctx-m-8) in cefotaxime-resistant enterobacteriaceae isolated in estimate the diversity of extended-spectrum beta-lactamases in brazil, 18 strains from different species of the family enterobacteriaceae exhibiting a positive double-disk synergy test were collected by a clinical laboratory from several hospitals in rio de janeiro, brazil, in 1996 and 1997. four strains (proteus mirabilis, enterobacter cloacae, enterobacter aerogenes, and citrobacter amalonaticus) hybridized with a 550-bp ctx-m probe. the p. mirabilis strain produced a ctx-m-2 enzyme. the e. ...200010858358
novel cefotaximase (ctx-m-16) with increased catalytic efficiency due to substitution asp-240-->gly.three clinical strains (escherichia coli rio-6, e. coli rio-7, and enterobacter cloacae rio-9) collected in 1996 and 1999 from hospitals in rio de janeiro (brazil) were resistant to broad-spectrum cephalosporins and gave a positive double-disk synergy test. two bla(ctx-m) genes encoding beta-lactamases of pl 7.9 and 8.2 were implicated in this resistance: the bla(ctx-m-9) gene observed in e. coli rio-7 and e. cloacae rio-9 and a novel ctx-m-encoding gene, designated bla(ctx-m-16), observed in e. ...200111451684
dissemination of blakpc-2 by the spread of cc258-klebsiella pneumoniae clones (st258, st11, st437) and plasmids (incfii, incn, incl/m) among enterobacteriaceae species in brazil.this study reports the spread of bla(kpc-2) in são paulo and rio de janeiro states facilitated by globally spread cc258-k. pneumoniae clones (st258, st11, st437) and a diversity of plasmids (incfii, incn, incl/m, two untypeable plasmids carrying tn4401a or tn4401b) successfully disseminated among enterobacteriaceae species (enterobacter cloacae, serratia marcescens and citrobacter freundii). it also constitutes the first description of st258 in brazil which was associated with a nosocomial hospi ...201121576442
multiresistance, beta-lactamase-encoding genes and bacterial diversity in hospital wastewater in rio de janeiro, brazil.aims:ôçé to investigate the bacterial diversity, antimicrobial resistance patterns and types of beta-lactamase genes in gram-negative bacteria isolated from a hospital sewage treatment plant. methods and results:ôçé between july and december 2008, we collected samples from influent, clarifier tank effluent and chlorine contact tank effluent from a sewage treatment plant service of a hospital located in the city of rio de janeiro, brazil. of the 221 isolates identified, 40% were characterized as ...201121672095
unusual association of ndm-1 with kpc-2 and arma among brazilian enterobacteriaceae isolates.we report the microbiological characterization of four new delhi metallo-β-lactamase-1 (blandm-1)-producing enterobacteriaceae isolated in rio de janeiro, brazil. blandm-1 was located on a conjugative plasmid and was associated with klebsiella pneumoniae carbapenemase-2 (blakpc-2) or aminoglycoside-resistance methylase (arma), a 16s rrna methylase not previously reported in brazil, in two distinct strains of enterobacter cloacae. our results suggested that the introduction of blandm-1 in brazil ...201425466163
clonal dissemination of oxa-370-producing klebsiella pneumoniae in rio de janeiro, brazil.enzymes of the oxa-48 family have become some of the most important beta-lactamases in the world. a new oxa-48 variant (oxa-370) was first described for an enterobacter hormaechei strain isolated in rio grande do sul (southern region of brazil) in 2013. here we report detection of the blaoxa-370 gene in 24 isolates belonging to three enterobacteriaceae species (22 klebsiella pneumoniae isolates, 1 enterobacter cloacae isolate, and 1 enterobacter aerogenes isolate) collected from five hospitals i ...201525987619
molecular epidemiology of ctx-m producing enterobacteriaceae isolated from bloodstream infections in rio de janeiro, brazil: emergence of ctx-m-15.the present study was designed to evaluate the molecular epidemiology of ctx-m producing klebsiella pneumoniae, enterobacter cloacae and escherichia coli isolated from bloodstream infections at tertiary care hospitals in the state of rio de janeiro, brazil.201324055309
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