Publications

outbreak of cephalosporin resistant enterobacter cloacae infection in a neonatal intensive care unit.	enterobacter cloacae resistant to third generation cephalosporins emerged rapidly during an outbreak of serious infections due to this organism in a neonatal intensive care unit where ampicillin and gentamicin were used as first line antibiotic treatment. organisms resistant to cephalosporins were isolated from 12 infants, six of whom developed systemic infection. two infants died. isolates of e. cloacae from four of five infants treated with cefotaxime showed a loss of sensitivity to this antib ...	1987	3827292
enterobacter cloacae in a neonatal intensive care unit: account of an outbreak and its relationship to use of third generation cephalosporins.	after uneventful use of cefotaxime and ceftazidime as first line therapy for three years in our neonatal intensive care unit we isolated cephalosporin-resistant enterobacter cloacae (crec) strains which caused clusters of cases or colonization and/or serious neonatal infection. by using two or more typing methods, at least five different strains with similar patterns of antimicrobial sensitivities were identified. the results of a case-control study did not support the notion that the use of thi ...	1994	7897189
bacteraemia in the adult intensive care unit of a teaching hospital in nottingham, uk, 1985-1996.	bacteraemia is an important cause of morbidity and mortality in the intensive care unit. in this study the distribution of organisms causing bacteraemic episodes in patients in the adult intensive care unit of a large teaching hospital was determined. particular emphasis was placed on the type of organisms isolated from community- and hospital-acquired bacteraemia, the suspected source of infection, the possible risk factors associated with bacteraemia, and outcome. the incidence of bacteraemia ...	1998	9758274
an outbreak of multiply resistant enterobacter cloacae in a neonatal intensive care unit.		2001	11428886
predominance and genetic diversity of community- and hospital-acquired ctx-m extended-spectrum beta-lactamases in york, uk.	this study was conducted to detect the presence of extended-spectrum beta-lactamase (esbl)-producing enterobacteriaceae within the faecal flora of both community- and hospital-based patients in york and to characterize the bla(tem), bla(shv) and bla(ctx-m) genes present in these isolates.	2004	15294889
high prevalence of the plasmid-mediated quinolone resistance determinant qnra in multidrug-resistant enterobacteriaceae from blood cultures in liverpool, uk.	to determine the prevalence of the plasmid-mediated quinolone resistance qnra gene in a selected collection of blood culture isolates of enterobacteriaceae resistant to both ciprofloxacin and cefotaxime.	2005	16260446
an outbreak of wound infection in cardiac surgery patients caused by enterobacter cloacae arising from cardioplegia ice.	this paper describes an outbreak of postoperative sternal wound infections. a cardiac surgeon noted a cluster of serious infections leading to wound dehiscence, despite the fact that none of his colleagues had noticed a rise in infection rates. the infections were predominantly with enterobacter cloacae, and molecular typing and serotyping showed these isolates to be indistinguishable. observation of the surgeon's practice revealed nothing untoward, and there were no infections among his patient ...	2006	16899327
prevalence of silver resistance in bacteria isolated from diabetic foot ulcers and efficacy of silver-containing wound dressings.	silver dressings are used to manage wounds at risk of infection or locally infected. this in vitro study was conducted to assess the prevalence of silver resistance genes in 112 bacterial isolates obtained from the diabetic foot ulcers of patients attending the diabetic foot clinic at tameside general hospital, uk. using polymerase chain reaction to screen for three silver-resistance transcriptional units--sile, sils and silp--two silver-resistant bacteria were identified; both are strains of en ...	2008	18382046