Publications

chlamydia pneumoniae, strain twar, as the cause of an outbreak in a boys' school previously called psittacosis.	sera from an outbreak of acute respiratory illness in a boys boarding school originally thought to have been due to psittacosis (1) have been re-examined and evidence is presented that suggests that the outbreak was caused by chlamydia pneumoniae, strain twar (2).	1989	2680550
a study of human respiratory tract chlamydial infections in cambridgeshire 1986-88.	human respiratory tract chlamydial infections have been studied in cambridgeshire for many years, but until recently we have been unable to distinguish between infection with chlamydia psittaci or chlamydia pneumoniae (twar). in this study, we have employed the micro-immunofluorescence (micro-if) test for this purpose and to look for the relative incidence of c. psittaci and c. pneumoniae infections in cambridgeshire. among 50 patients with community-acquired respiratory tract symptoms whose ser ...	1990	2347386
antibodies to chlamydia species in patients attending a genitourinary clinic and the impact of antibodies to c. pneumoniae and c. psittaci on the sensitivity and the specificity of c. trachomatis serology tests.	in a retrospective study, the prevalence of antibodies to chlamydia trachomatis serovars d to k, c. pneumoniae, and c. psittaci in cases attending a genitourinary clinic was examined. blood samples were collected from 7,002 cases attending the clinic in doncaster, england between may 1983 and may 1990. sera from these samples were tested by a modified microimmunofluorescence test using panels of microdots of egg-grown, purified elementary bodies representing a pool of c. trachomatis d to k, a si ...	1993	8503060
chlamydial infection of the respiratory tract.	chlamydial infection of the human respiratory tract was first described over 100 years ago, when outbreaks of psittacosis were linked to imported pet birds. the causative organism was identified subsequently as chlamydia psittaci. however, c. pneumoniae, has also been recognised recently as an important cause of human respiratory tract infection. approximately 300 cases of human chlamydial respiratory tract infection are reported to cdsc each year, mainly in adults aged 15 to 44 years. a prospec ...	1993	7693170
respiratory chlamydia: the management of an outbreak.	this investigation was undertaken in response to the occurrence of nine cases of respiratory chlamydial infection in 8 months within the district of dudley. all nine cases of respiratory chlamydia were due to chlamydia psittaci, not chlamydia pneumoniae. five cases had avian exposure, but no other aetiological factors were identified. faecal specimens were obtained from only two of the implicated birds and were negative. two local aviaries were identified as sources of implicated birds. the two ...	1995	7597134
the etiology of community-acquired pneumonia among hospitalized patients during a chlamydia pneumoniae epidemic in finland.	the etiology of community-acquired pneumonia during a chlamydia pneumoniae epidemic was studied among 125 hospitalized patients. etiologic investigations included blood and sputum cultures, pneumococcal antigen detection, and serologic investigations for common respiratory viruses and for streptococcus pneumoniae, haemophilus influenzae, moraxella catarrhalis, mycoplasma pneumococcal antigen detection, and serologic investigations for common and for streptococcus pneumoniae, haemophilus influenz ...	1995	7594672
chlamydia pneumoniae and acute arterial thrombotic disease.		1995	7586293
association of helicobacter pylori and chlamydia pneumoniae infections with coronary heart disease and cardiovascular risk factors.	to investigate the relation between seropositivity to chronic infections with helicobacter pylori and chlamydia pneumoniae and both coronary heart disease and cardiovascular risk factors.	1995	7549683
chlamydia pneumoniae: risk factors for seropositivity and association with coronary heart disease.	two studies have suggested that seropositivity for chlamydia pneumoniae (c. pneumoniae) is a risk factor for coronary heart disease (chd) but the association remains tenuous. further data is required in other populations to consolidate this observation.	1995	7636277
c reactive protein and its relation to cardiovascular risk factors: a population based cross sectional study.	to test the hypothesis that minor chronic insults such as smoking, chronic bronchitis, and two persistent bacterial infections may be associated with increases in c reactive protein concentration within the normal range and that variations in the c reactive protein concentration in turn may be associated with levels of cardiovascular risk factors and chronic coronary heart disease.	1996	8616412
chlamydia pneumoniae antibody titers are significantly associated with acute stroke and transient cerebral ischemia: the west birmingham stroke project.	several studies have implied an association between chlamydia pneumoniae and atherosclerosis. our research was designed to investigate the association of this organism with strokes and transient cerebral ischemia.	1998	9472881
chlamydia pneumoniae infection and ethnic origin.	to test the association of chlamydia pneumoniae infection with ethnic origin.	1998	10403105
strong correlation between helicobacter pylori seropositivity and chlamydia pneumoniae igg concentrations.		1998	10396525
is infection control an academic study?	this editorial aims to answer the question of whether infection control is an academic specialty. by considering the consequences of a lack of infection control in terms of patient morbidity and mortality and hence cost, it is easy to establish the importance of the area. infection control embraces not only developing policies for preventing the physical spread of a micro-organism but also prophylactic therapy such as vaccination and therapeutic measures such as antibiotics. infection control no ...	1999	9949958
rationalised prescribing for community acquired pneumonia: a closed loop audit.	to audit the management of community acquired pneumonia before and after the introduction of a protocol. to determine the aetiology of pneumonia using routine investigations and polymerase chain reaction (pcr).	2000	10999868
chlamydia pneumoniae infection and mortality from ischaemic heart disease: large prospective study.	to determine whether there is an independent association between infection with chlamydia pneumoniae and ischaemic heart disease.	2000	10903649
the association between deaths from myocardial infarction and household size in england and wales.	chronic infection with organisms such as chlamydia pneumoniae is thought to cause coronary heart disease. we investigated whether myocardial infarction deaths are associated with large household size and overcrowding, as these are factors that may facilitate the transmission of infection.	2001	11455848
chlamydia pneumoniae in elderly patients with stroke (c-peps): a case-control study on the seroprevalence of chlamydia pneumoniae in elderly patients with acute cerebrovascular disease.	multiple studies have suggested an association between chlamydia pneumoniae infection and atherosclerotic vascular disease. we investigated whether serological markers of c. pneumoniae infection were associated with acute stroke or transient ischaemic attack (tia), exclusively in elderly patients.	2003	12499705
mycoplasma pneumoniae in elderly patients with stroke. a case-control study on the seroprevalence of m. pneumoniae in elderly patients with acute cerebrovascular disease - the m-peps study.	previous studies have suggested certain infections as potential risk factors for stroke. chlamydia pneumoniae, an atypical respiratory pathogen, has been linked to atherosclerotic vascular diseases. mycoplasma pneumoniae, another atypical respiratory micro-organism, can rarely cause stroke. we investigated whether serological markers of m. pneumoniae infection were associated with acute stroke or transient ischaemic attack (tia) in elderly patients.	2004	15026614
detection of simkania negevensis by culture, pcr, and serology in respiratory tract infection in cornwall, uk.	respiratory tract infections are often treated empirically without investigation to detect the aetiological agent, which may be a virus or a bacterium, including atypical pathogens such as chlamydophila pneumoniae or mycoplasma pneumoniae. recently, several types chlamydia-like intracellular bacteria have been detected in environmental samples and clinical specimens. little is known of their geographical distribution and potential pathogenicity. we describe the detection, by pcr and isolation in ...	2006	16505289
socioeconomic status, pathogen burden and cardiovascular disease risk.	socioeconomic status (ses) is inversely associated with coronary heart disease (chd) risk. cumulative pathogen burden may also predict future chd. the hypothesis was tested that lower ses is associated with a greater pathogen burden, and that pathogen burden accounts in part for ses differences in cardiovascular risk factors.	2007	17488763