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collaborative study of temperature-sensitive mutants of herpes simplex virus type 2.eighteen complementation groups were identified by complementation tests and by phenotype from twenty temperature-sensitive mutants isolated independently in glasgow, scotland, and houston, tex.1976178919
genital herpes simplex virus type 1 in women: detection in cervicovaginal specimens from gynecological practices in the united states.herpes simplex virus types 1 and 2 (hsv-1 and -2) are significant human pathogens causing clinically indistinguishable facial and genital lesions. recently, the number of reported genital herpes cases caused by type 1 virus has increased. identifying the hsv type is of clinical importance to determine proper treatment, as there is no licensed vaccine or cure. we assessed, by pcr, the frequency of hsv-1 and hsv-2 present in more than 60,000 clinical cervicovaginal specimens derived from samples o ...201019923487
prevalence of sexually transmitted infections and associated risk factors among populations of drug abusers.a cross-sectional survey was conducted of sexually transmitted diseases (stds) and risky behaviors among 407 drug abusers in treatment facilities in 1998. infections with human immunodeficiency virus (hiv), hepatitis b virus (hbv), hepatitis c virus (hcv), herpes simplex virus type 2 (hsv-2), and syphilis were detected by testing serum antibody levels; chlamydia and gonorrhea were detected by testing nucleic acid levels in urine. logistic regression analysis was performed to measure associations ...200011049771
a prospective study of herpes simplex virus infection in a defined population in houston, texas.a seroepidemiologic study was conducted to determine the incidence of antibodies to herpes simplex virus in a population of middle-class caucasian women. in utero exposure to diethylstilbestrol did not influence the frequency of herpes simplex virus infection. the frequency of infection increased with age and number of sex partners and a 50% increase in incidence of herpes simplex virus type 2 infection was noted during the 4-year period of the study. subclinical herpes simplex virus type 2 infe ...19852983557
sexual behaviour, stds and drug use in a crack house population.we aimed to investigate the prevalence of ulcerative sexually transmissible diseases (stds) and hepatitis in crack users. we interviewed 435 crack users on site in crack houses in houston, texas and took blood for laboratory analysis. there was evidence of syphilis infection in 13%, herpes simplex virus-2 (hsv-2) in 61%, hiv in 12%, hepatitis b in 52%, and hepatitis c in 41% of cases. on dsm-iii-r criteria, 12% were crack abusers and 84% crack dependent: over half reported previous treatment. fo ...199912035774
epidemiological studies relating genital herpetic infection to cervical carcinoma.epidemiological studies relating genital herpetic infection to cervical carcinoma are reviewed. the high frequency of herpes simplex virus type 2 (hsv-2) antibodies in young women (21 years or younger) with cervical carcinoma in situ and in women with dysplasia or carcinoma in situ, matched for various sexual attributes to control women, provide support for a causal relation. however, various laboratory, histopathological, and statistical problems associated with all epidemiological studies do ...19744366985
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