restriction endonuclease cleavage analysis of herpes simplex virus type 2 from chiang mai, thailand and okinawa, japan. | genomic variations of herpes simplex viruses type 2 (hsv 2) isolated from chiang mai, thailand and okinawa, southernmost part of japan were studied. the genomic polymorphism of 40 hsv 2 chiang mai strains and 10 hsv 2 okinawan strains was analyzed by means of the variations of cleavage sites and electrophoretic mobilities of dna fragments after digestion with 4 restriction endonucleases (re (bamh i, kpn i, ecor i, and bgl ii)). using the main 6 variable re cleavage sites, hsv 2 strains were clas ... | 1995 | 7631121 |
pathologic studies and comparison of the virulence of herpes simplex virus type 2 from okinawa, japan and chiang mai, thailand. | the virulence of four herpes simplex virus type 2 (hsv 2) strains (k1-k4) isolated in okinawa, japan was investigated, and compared with four strains (c1-c4) from chiang mai, thailand and a standard laboratory strain sav. virulence was tested on balb/c and c57/black mice. after viral inoculation intraperitoneally, the distribution with the passage of time of the virus in the brain and other organs was also studied using the polymerase chain reaction (pcr) method and immunohistochemistry. general ... | 1995 | 7547439 |