an epidemiological survey of infectious necrotic hepatitis (black disease) of sheep in southern scotland. 19734591586
the prophylaxis of ovine fascioliasis by the strategic use of rafoxanide. 19734693386
studies on helminthosis at the centre for tropical veterinary medicine (ctvm).the research work relating to helminths, which has been conducted within the helminthology section of the ctvm, often in collaboration with colleagues from the tropics is reviewed and placed into a historical perspective. the research has, in the main, concentrated on the trematodes fasciola hepatica and fasciola gigantica and the cestodes taenia saginata and taenia solium, but work on other parasites including gastro-intestinal nematodes is also considered. all of these parasites are of obvious ...19968815611
sheep helminth parasitic disease in south eastern scotland arising as a possible consequence of climate change.the climate in the uk is changing, with a trend towards increased rainfall in the autumn and winter and warmer average temperatures throughout the year. there has also been a 4-week extension of the herbage growing season over the past 40 years. these changes may have implications for the epidemiology of sheep helminth parasites. here, we describe production-limiting disease outbreaks caused by haemonchus contortus, nematodirus battus, teladorsagia circumcincta and fasciola hepatica in sheep flo ...200919556065
on farm evaluation of the coproantigen elisa and coproantigen reduction test in scottish sheep naturally infected with fasciola hepatica.the liver fluke, fasciola hepatica, is a cause of significant economic losses in sheep farming. lack of convenient and sensitive diagnostic tests in the live animal hampers the ability to monitor infection status and treatment efficacy. use of a coproantigen elisa and coproantigen reduction test, based on this elisa, may address these issues but has, to date, only been evaluated in experimental challenge studies. we evaluated the coproantigen elisa under working farm conditions in scotland to as ...201222421492
identification of the rumen fluke, calicophoron daubneyi, in gb livestock: possible implications for liver fluke diagnosis.the liver fluke, fasciola hepatica, is common in many parts of great britain. to detect liver fluke infection and to assess whether fasciolicide treatment has been successful, the faecal egg count (fec) and faecal egg count reduction test (fecrt) are widely used. rumen fluke is also increasingly reported from great britain, but its species identity is yet to be determined. liver fluke and rumen fluke eggs are morphologically similar, which may lead to erroneous diagnoses of liver fluke infection ...201323411375
evaluation of the performance of five diagnostic tests for fasciola hepatica infection in naturally infected cattle using a bayesian no gold standard approach.the clinical and economic importance of fasciolosis has been recognised for centuries, yet diagnostic tests available for cattle are far from perfect. test evaluation has mainly been carried out using gold standard approaches or under experimental settings, the limitations of which are well known. in this study, a bayesian no gold standard approach was used to estimate the diagnostic sensitivity and specificity of five tests for fasciolosis in cattle. these included detailed liver necropsy inclu ...201627564546
levels of liver fluke disease in scottish livestock expected to remain high. 201122235444
the incidence of helminth parasites from the wild rabbit oryctolagus cuniculus (l.) in eastern scotland.samples of wild rabbits were collected each month over the six-year period 1977-82 and their intestines and abdomens examined for helminths. three species of nematode, four of cestode and one trematode were found. graphidium strigosum was recorded in 33% of the 786 rabbits, trichostrongylus retortaeformis in 79%, passalurus ambiguus in 14.2%, cittotaenia pectinata in 37%, c. denticulata in 11%, coenurus pisiformis in 3%, cysticercus serialis in 0.1% and fasciola hepatica in 0.1%. g. strigosum an ...19853989265
liver fluke in great britain: a survey of affected livers.over a period of 15 months data were collected from abattoirs in great britain on 213,082 cattle and 362,838 sheep livers to determine the distribution and prevalence of damage by fasciola hepatica. the stock came from 8239 farms, and from livestock markets in 81 counties. 53 per cent of the farms had sent affected stock, with significant percentages in eastern as well as the western counties of england and scotland. 21 per cent of all cattle and 7 per cent of all sheep livers examined were affe ...19751202744
a study of a strategic dosing programme against ovine fascioliasis on a hill a farm-scale veterinary preventive programme run from 1973 to 1976 the use of rafoxanide (flukanide; merck sharp & dohme) in the prophylaxis of ovine fascioliasis resulted in a marked reduction in the percentage of ewes passing fluke eggs in the faeces and an absence of clinical cases of fascioliasis throughout these years. three separate flocks of hill sheep were used in this study in which the aim of the dosing programme followed was to kill the majority of liver flukes (fasciola hepatica) ...1977878250
diagnosis and economic consequences of triclabendazole resistance in fasciola hepatica in a sheep flock in south-east scotland.over the past decade, definite changes have been recorded in the regional prevalence, seasonality and severity of fasciolosis in the uk, related to increased rainfall, or localised flooding, prompting debate about the deleterious effects of climate change. as a consequence, effective management of fasciolosis has become problematic in areas where fluke traditionally exists, leading to serious loss of production in sheep and cattle. meanwhile, in eastern districts, there have been unexpected outb ...201121493511
Use of diagnostic markers to monitor fasciolosis and gastrointestinal nematodes on an organic dairy farm.A 12-month study was conducted to assess and monitor gastrointestinal tract nematodes and liver fluke in cohorts of cattle on a Scottish organic dairy farm. Various diagnostic markers for helminth parasites of cattle from different age groups were assessed monthly from April 2007 to March 2008. First season grazing stock were subjected to significant challenge from Ostertagia ostertagi nematodes as reflected in serum pepsinogen concentrations, which rose markedly in the second half of the grazin ...201121908552
prevalence of liver fluke (fasciola hepatica) in wild red deer (cervus elaphus): coproantigen elisa is a practicable alternative to faecal egg counting for surveillance in remote deer (cervus elaphus) are hosts of liver fluke (fasciola hepatica); yet, prevalence is rarely quantified in wild populations. testing fresh samples from remote regions by faecal examination (fe) can be logistically challenging; hence, we appraise frozen storage and the use of a coproantigen elisa (celisa) for f. hepatica surveillance. we also present celisa surveillance data for red deer from the highlands of scotland. diagnoses in faecal samples (207 frozen, 146 fresh) were compared using a ...201627598003
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