| detection of chandipura virus from sand flies in the genus sergentomyia (diptera: phlebotomidae) at karimnagar district, andhra pradesh, india. | a total of 191 adult sand flies belonging to the genus sergentomyia were collected from seven villages in karimnagar and warangal districts of andhra pradesh state, india, after an outbreak of encephalitis due to chandipura virus (chpv). fifteen pools, each containing two specimens, were tested by reverse transcriptase-polymerase chain reaction and sequencing. one pool of sergentomyia from kolanur village in karimnagar district was positive for chpv. | 2005 | 15962804 |
| chandipura virus: a major cause of acute encephalitis in children in north telangana, andhra pradesh, india. | a hospital-based surveillance was undertaken between may 2005 and april 2006 to elucidate the contribution of chandipura virus (chpv) to acute viral encephalitis cases in children, seroconversion in recovered cases and to compare the seroprevalences of anti-chpv igm and n antibodies in areas reporting cases with those without any case of acute viral encephalitis. during this period, 90 cases of acute encephalitis were hospitalized in the pediatric wards of mahatma gandhi memorial (mgm) hospital, ... | 2008 | 18041027 |
| development and evaluation of a real-time one step reverse-transcriptase pcr for quantitation of chandipura virus. | chandipura virus (chpv), a member of family rhabdoviridae was attributed to an explosive outbreak of acute encephalitis in children in andhra pradesh, india in 2003 and a small outbreak among tribal children from gujarat, western india in 2004. the case-fatality rate ranged from 55-75%. considering the rapid progression of the disease and high mortality, a highly sensitive method for quantifying chpv rna by real-time one step reverse transcriptase pcr (real-time one step rt-pcr) using taqman tec ... | 2008 | 19091082 |
| changing clinical scenario in chandipura virus infection. | chandipura virus (chpv) (vesiculovirus: rhabdoviridae) garnered global attention as an emerging neurotropic pathogen inflicting high mortality in children within 24 h of commencement of symptoms. the 2003-2004 outbreaks in central india witnessed case fatality rates ranging from 56-75 per cent in andhra pradesh and gujarat with typical encephalitic symptoms. due to the acute sickness and rapid deterioration, the precise mechanism of action of the virus is still unknown. recent studies have shown ... | 0 | 27748295 |
| a large outbreak of acute encephalitis with high fatality rate in children in andhra pradesh, india, in 2003, associated with chandipura virus. | an outbreak of acute encephalitis of unknown origin with high case fatality (183 of 329 cases) was reported in children from andhra pradesh state in southern india during 2003. we investigated the causative agent. | 2004 | 15351194 |
| brainstem encephalitis associated with chandipura in andhra pradesh outbreak. | clinical data of 104 hospitalized children during the 2003 epidemic of encephalitis in andhra pradesh state was retrospectively analysed to know the clinical profile and risk factors associated with mortality. fever was the first symptom associated with altered sensorium, seizures, diarrhoea and vomiting. evolution of illness was very rapid with high fatality (47%). majority of deaths occurred within the first 24 h of illness due to brainstem involvement. on multiple logistic regression analysis ... | 2008 | 17906316 |
| an outbreak of chandipura virus encephalitis in the eastern districts of gujarat state, india. | an outbreak of encephalitis with a case fatality rate of 78.3% was investigated among children in gujarat state, india. twenty-six cases were reported. three patients had igm antibodies to chandipura virus. virus was isolated from one patient with rhabdomyosarcoma in porcine stable cell lines and in suckling mice. chandipura virus rna was present in 9 of 20 acute-phase serum samples, and virus sequences from the present outbreak were closely related to prototype strain (1965) and andhra pradesh, ... | 2005 | 16172482 |
| incidence of neutralizing antibodies to chandipura virus in domestic animals from karimnagar and warangal districts of andhra pradesh, india. | in order to determine the possible role of domestic animals in the outbreak of acute encephalitis associated with chandipura virus (cpv) among children in andhra pradesh in 2003, a serological survey of domestic animals was carried out during the epidemic in july 2003. out of 180 animal sera from highly affected areas of the karimnagar and warangal districts of andhra pradesh 33 (18.3%) had virus neutralizing (vn) antibodies to cpv. the positive animals consisted of pigs (30.6%), buffalos (17.9% ... | 2005 | 15929402 |