Publications

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[current recrudescence of human trypanosomiasis in the sangha focus (basin) in the congo].in the congo the sangha focus of sleeping sickness caused more than 500,000 deaths in the early 20th century. despite many years of quiescence many new cases have been detected since the early eighties. in 1987 an investigation found 43 infected patients within 5 villages (during the same year, 74 cases were detected from both investigation and passive detection). in december 1989 our further investigation found 96 new documented cases (115 for the whole year). the prevalence is increasing and t ...19921596955
[interpretation of the catt (card agglutination trypanosomiasis test) in the screening for human trypanosomiasis due to trypanosoma brucei gambiense].mass screening for gambiense sleeping sickness is usually done with the card agglutination trypanosomiasis test (catt) in series (total blood catt followed by a serum catt if the first test is positive) and the search for trypanosomes in cervical adenopathies. at present, the double positives (blood catt and serum catt) as well as the subjects in whom the trypanosome was found (in the blood or gland juice) are treated. the existence of patients whose gland punction was proved positive whereas th ...19911958107
[socio-entomologic survey in human trypanosomiasis focus of yamba (peoples republic of congo)].a study carried out at villagers level in a focus infected by human trypanosomiasis (yamba, bouenza region, congo, mikengue ethnic group) revealed that modern medicin is recognized by them as the sole possibility to treat the sleeping sickness. the witch doctor, if he cannot transmit the sickness, is perfectly able to aggravate it. he is considered as the responsible for any fatal issue. tsetse flies are charged of transmitting the sickness as well as other biting insects (black flies, ceratopog ...19854068972
nifurtimox-eflornithine combination therapy for second-stage trypanosoma brucei gambiense sleeping sickness: a randomized clinical trial in congo.human african trypanosomiasis caused by trypanosoma brucei gambiense is a fatal disease. current treatment options for patients with second-stage disease are either highly toxic or impracticable in field conditions. we compared the efficacy and safety of the nifurtimox-eflornithine drug combination with the standard eflornithine regimen for the treatment of second-stage disease.200717990225
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