| evidence for the occurrence of trypanosoma brucei rhodesiense sleeping sickness outside the traditional focus in south-eastern uganda. | the occurrence of trypanosoma brucei rhodesiense west of the river nile, in masindi district in the mid-western part of uganda, is confirmed. masindi borders the traditional belt of t. b. gambiense infection in the north-west, gulu in the north and the democratic republic of congo in the west. of the 702 persons tested for sleeping sickness in masindi, 113 (16%) were positive by the card agglutination test for trypanosomiasis (catt). trypanosomes were observed in samples of cerebrospinal fluid ( ... | 1999 | 10715675 |
| risk factors for treatment failure after melarsoprol for trypanosoma brucei gambiense trypanosomiasis in uganda. | we evaluated the treatment failure rate among late-stage human african trypanosomiasis (hat) patients treated with melarsoprol in arua, northern uganda, between september 1995 and august 1996, and identified the risk factors for treatment failure. we conducted a retrospective cohort study in october 1998, and performed a survival analysis. a treatment failure was defined as a late-stage hat patient fully treated with melarsoprol and classified as an hat case at any follow-up visit within 2 years ... | 1999 | 10674099 |
| key indicators for the monitoring and evaluation of control programmes of human african trypanosomiasis due to trypanosoma brucei gambiense. | very little research has been devoted to the design of epidemiological tools for the monitoring and evaluation of national human african trypanosomiasis (hat) control programmes and daily management decisions are made in the absence of accurate knowledge of the situation. this paper identifies key indicators necessary to make decisions in the field and constantly adjust control activities to changing situations. examples are derived from the médecins sans frontières (msf) hat control programme i ... | 1998 | 9657510 |
| [trypanosomiasis from trypanosoma brucei gambiense in the center of north-west uganda. evaluation of 5 years of control (1987-1991)]. | in uganda, a case-finding and treatment programme has been implemented by médecine sans frontières (msf) and the ministry of health in the north of west-nile province. data collected in the hospital of moyo from january 1987 to june 1991 were analyzed. forty eight hundred and twenty two cases of trypanosomiasis due to t. b. gambiense has been recorded. cumulative incidence rate for this period was 5.6%. passive and active case-finding strategies were used, both based on card agglutination test ( ... | 1995 | 7787452 |
| isolation of trypanosoma brucei gambiense from northern uganda: evaluation of the kit for in vitro isolation (kivi) in an epidemic focus. | 867 individuals from 3 sites near the town of adjumani in the east moyo region of north-west uganda were investigated clinically and serologically for evidence of current trypanosome infections. blood samples were taken from 94 persons with a positive card agglutination test for trypanosomiasis (catt) and clinical suspects and inoculated into the kit for in vitro isolation of trypanosoma brucei gambiense (kivi). amongst this group, 30 parasitaemic individuals were identified by microhaematocrit ... | 1995 | 7570873 |