| aseptic meningitis after vaccination with l-zagreb mumps strain-virologically confirmed cases. faulty calculation of rates. | in a letter to the editor published in vaccine recently (vaccine 24 (2006) 6371-6373), the authors describe clinical features of vaccine associated aseptic meningitis (am) of patients hospitalized in one hospital, proceeding to calculate incidence rates of am based on hospital admission data. since the denominator for hospital-based cases is unknown, the incidence rates calculated in such a way are methodologically incorrect and should not be considered relevant. | 2007 | 17092613 |
| genetic heterogeneity of l-zagreb mumps virus vaccine strain. | the most often used mumps vaccine strains jeryl lynn (jl), rit4385, urabe-am9, l-zagreb and l-3 differ in immunogenicity and reactogenicity. previous analyses showed that jl, urabe-am9 and l-3 are genetically heterogeneous. | 2008 | 18616793 |
| transmission of the l-zagreb mumps vaccine virus, croatia, 2005-2008. | we report on three cases of symptomatic transmission of the l-zagreb mumps vaccine virus from three vaccinated children to five adult contacts. the five contact cases were parents of the vaccinated children and presented with parotitis and in one case also with aseptic meningitis. the etiology of the contacts' illness was determined by viral culture, genomic sequencing, serology and epidemiological linking. two of the vaccinated children developed vaccine associated parotitis as an adverse event ... | 2008 | 18768116 |