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full spectrum of clinical, serological, and epidemiological features of complicated forms of lyme borreliosis in the paris, france, area.the aim of this study was to report the clinical, serological and epidemiological features of a homogeneous cohort of patients with various forms of lyme borreliosis, based on recent european case-definition guidelines. complete clinical and epidemiological reports were requested from the patients' physicians for case definition. enzyme immunoassay igg and igm screening tests were performed. a total of 170 patients (141 adults and 29 children) with the following forms of lyme borreliosis were in ...200011152304
density of deer in relation to the prevalence of borrelia burgdorferi s.l. in ixodes ricinus nymphs in rambouillet forest, france.the rambouillet forest, a lyme disease-endemic area near paris, france, was surveyed from september 1994 to october 1995 to determine the risk periods and zones for humans. firstly, during the period of ixodes ricinus activity, abundance of nymphs is greater in spring than in autumn. secondly, we observed significant variation in nymphal abundance between zones according to the density of cervids. the polymerase chain reaction (pcr) was used to detect dna of borrelia burgdorferi sensu lato in 46 ...199910356769
[negativity of borrelia burgdorferi serology in scleroderma en plaques].the occurrence of morphea has been attributed to borrelia, burgdorferi infection, but the relationship between localised scleroderma and borreliosis remains controverted. antibodies directed against b. burgdorferi were looked for in 21 patients (18 female and 3 male, aged from 8 to 63 years) whose disease had been present for 6 weeks to 13 years. one patient had a single morphea, two had monomelic scleroderma and 18 had multiple localised morpheas. the search for antibodies was conducted in thes ...19892688515
prevalence of antibodies to borrelia burgdorferi in forestry workers of ile de france, france.a cross-sectional sero-epidemiological study was conducted on forestry workers, a high risk population for lyme borreliosis. the prevalence of seropositive forestry workers (indirect immuno fluorescence assay) is 15.2% (n = 211). almost 70% of participants reported a history of tick bite. among districts, high seroprevalences were observed in fontainebleau and rambouillet; two sites of high risk for lyme borreliosis. however, clinical prevalence of the disease is very low. during the investigati ...19979476828
infection of ixodes ricinus (acari:ixodidae) by borrelia burgdorferi in ile de france.free-living nymphs and adults from rambouillet and fontainebleau, 2 major forests of ile de france, were collected to determine the infection rates of ixodes ricinus l. by borrelia burgdorferi (johnson, schmid, hyde, steigerwalt & brenner). field-collected i. ricinus nymphs and adults were screened for the presence of b. burgdorferi using direct fluorescent antibody assay. the infection rates of nymph, male and female were 12.4% (314), 2.8% (35), and 2.9% (34). no difference in infection rates o ...19968699470
multiple independent transmission cycles of a tick-borne pathogen within a local host community.many pathogens are maintained by multiple host species and involve multiple strains with potentially different phenotypic characteristics. disentangling transmission patterns in such systems is often challenging, yet investigating how different host species contribute to transmission is crucial to properly assess and manage disease risk. we aim to reveal transmission cycles of bacteria within the borrelia burgdorferi species complex, which include lyme disease agents. we characterized borrelia g ...201627498685
mapping human risk of infection with borrelia burgdorferi sensu lato, the agent of lyme borreliosis, in a periurban forest in france.lyme borreliosis is a major zoonosis in europe, with estimates of over 26,000 cases per year in france alone. the etiological agents are spirochete bacteria that belong to the borrelia burgdorferi sensu lato (s. l.) complex and are transmitted by hard ticks among a large range of vertebrate hosts. in europe, the tick ixodes ricinus is the main vector. in the absence of a vaccine and given the current difficulties to diagnose and treat chronic lyme syndromes, there is urgent need for prevention. ...201626897396
which forest bird species are the main hosts of the tick, ixodes ricinus, the vector of borrelia burgdorferi sensu lato, during the breeding season?wild birds are important hosts for vector-borne pathogens, especially those borne by ticks. however, few studies have been conducted on the role of different bird species within a community as hosts of vector-borne pathogens. this study addressed individual and species factors that could explain the burden of ixodes ricinus on forest birds during the reproductive periods of both vectors and hosts. the goal was to identify which bird species contribute the most to the tick population at the commu ...201222732161
introduced siberian chipmunks (tamias sibiricus barberi) contribute more to lyme borreliosis risk than native reservoir rodents.the variation of the composition in species of host communities can modify the risk of disease transmission. in particular, the introduction of a new host species can increase health threats by adding a new reservoir and/or by amplifying the circulation of either exotic or native pathogens. lyme borreliosis is a multi-host vector-borne disease caused by bacteria belonging to the borrelia burgdorferi sensu lato complex. it is transmitted by the bite of hard ticks, especially ixodes ricinus in eur ...201323383170
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